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What is outcome research?
What is an outcome measure?
How are outcome measures used in clinical practice?
What is a patient reported outcome measure?
An outcome measure, endpoint, effect measure or measure of effect is a measure within medical practice or research, (primarily clinical trials) which is used to assess the effect, both positive and negative, of an intervention or treatment.
May 10, 2024 · It discusses the features of outcome measures and provides a comparison between true outcome measures and surrogate outcome measures. All outcome measures fall into three basic categories: counting people (categorical data), taking measurements on people (continuous data), and time-to-event data.
Outcomes (also called events or endpoints) are variables that are monitored during a study to document the impact that a given intervention or exposure has on the health of a given population. Typical examples of outcomes are cure, clinical worsening, and mortality.
- Juliana Carvalho Ferreira, Cecilia Maria Patino, Cecilia Maria Patino
- 2017
- 1 The Comet Initiative
- 2 Rehabilitation Measures Database
- 3 Patient Reported Outcome Measurement Group
- 4 PROQOLID
- 5 OMERACT
The COMET initiative focuses on effectiveness trials and brings together a core outcome set (COS) of minimum outcome measures which should be reported in clinical trials of a specific condition. It also explains problems and key issues in using outcome measures in research. This database (http://www.comet-initiative.org/) is endorsed by the Europea...
This is a privately held and free to search database of outcome measures associated with rehabilitation which are predominantly questionnaire based. This database (https://www.sralab.org/rehabilitation-measures) gives an overview of the listed outcome measures including the time expected to complete and costs of the licence. It is organised by asse...
This PROM group is based at the University of Oxford. The website (http://phi.uhce.ox.ac.uk/home.php) includes guidance on the selection of appropriate outcome measures for use in clinical trials, practice, and population surveys. It is no longer supported with updates but it is still a useful resource.
This database (https://eprovide.mapi-trust.org/about/about-proqolid) provides information on over 2000 clinical outcome assessment tools. There are two levels of access; free and subscription. The free version provides basic information on outcome measures including the therapeutic area, indication, and bibliographic references for the description...
Outcome Measures in Rheumatology (OMERACT) is an online database of outcome measures pertinent to rheumatoid diseases (https://omeract.org/) as well as clinical and radiographic outcome measures . There is a heavy emphasis on patient involvement in endorsing outcome measures and advice on how to select an appropriate outcome measure.
- Fiona Mellor, Karen Knapp
- 2020
Jun 1, 2015 · The measures chosen to assess the impact of the interventions are called the outcome measures in the trial (or the trial endpoints). Such measures should be defined at the time the trial is designed and should be specified in detail in the study protocol.
- Peter G. Smith, Richard H. Morrow, David A. Ross
- 2015/06/01
- 2015
This chapter provides an overview of considerations for the development of outcome measures for observational comparative effectiveness research (CER) studies, describes implications of the proposed outcomes for study design, and enumerates issues of bias that may arise in incorporating the ascertainment of outcomes into observational research ...
Dec 24, 2020 · Outcome research is often characterised by the use of outcome measures, designed to identify the changes that take place during therapy. These contrast with process measures, which aim to identify the variables that cause these changes.
