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A major interest is to elucidate and manipulate mechanisms that control the expression of genes (either transcription, or translation). We are particularly interested in the role of non-canonical nucleic acid structures that control gene expression (e.g. G-quadruplexes, micro RNA and RNA structures in the 5' untranslated regions of mRNAs).
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Sir Shankar Balasubramanian FRS is an Indian-born British chemist and the Herchel Smith Professor of Medicinal Chemistry in the Yusuf Hamied Department of Chemistry at the University of Cambridge, Senior Group Leader at the Cancer Research UK Cambridge Institute and Fellow of Trinity College, Cambridge.
Shankar Balasubramanian is an internationally recognised leader in the field of nucleic acids who is distinguished for pioneering contributions to chemistry and its application to the biological and medical sciences.
Jul 29, 2022 · In 2012, Balasubramanian launched Cambridge Epigenetix, a company developing technologies that sense DNA methylation and other modifications of DNA’s four nucleotide bases during sequencing.
One of Professor Balasubramanian’s major research interests is to elucidate and manipulate mechanisms that control the expression of genes (either transcription, or translation). He is particularly interested in the role of non-canonical nucleic acid structures that control gene expression.
Shankar Balasubramanian's 383 research works with 40,092 citations and 16,745 reads, including: A Photoredox Reaction for the Selective Modification of 5-Carboxycytosine in DNA
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Aug 8, 2022 · In 2012, Balasubramanian launched Cambridge Epigenetix, a company developing technologies that sense DNA methylation and other modifications of DNA’s four nucleotide bases during sequencing. He has stayed in academia and continued working on many of the fundamental questions related to the structure of DNA molecules.
