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  1. Oct 2, 2018 · From AFL player Jarryd Roughead to businessman Ron Walker, to former US president Jimmy Carter, anecdotes abound for the activity of immune checkpoint inhibitors in advanced cancers such as...

  2. Jun 7, 2012 · It takes time for the deleterious effects of the thousands of carcinogenic chemicals in tobacco to dissipate, and it was not until 1990 that the incidence of lung cancer in men began to decline, followed by a decline in lung-cancer mortality beginning in 1991.

    • Vincent T. DeVita, Steven A. Rosenberg
    • 10.1056/NEJMra1204479
    • 2012
    • 2012/06/06
  3. From AFL player Jarryd Roughead to businessman Ron Walker, to former US president Jimmy Carter, anecdotes abound for the activity of immune checkpoint inhibitors in advanced cancers such as...

  4. Oct 2, 2018 · Cancer cells use these immune checkpoints to hide and evade from immune cells, tipping the balance in favour of the cancer and turning each immune cell off. Checkpoint inhibitor drugs work by...

    • CANCER March 15 Supplement 1991
    • Diagnosis and Staging
    • Past Attempts at Rationing
    • Current Rationing Techniques
    • How will health care be rationed in the 1990s if the medical profession does not somehow alter the course of events? One of the most chilling forecasts appeared 10 The Wall Street Journal59:
    • Ellwood74 suggested that the third party payers may be the first to possess information on effectiveness based on a study of claims data:

    suggests that immunization against carcinogens may be possible.24 The tools may soon be in hand to deal with high-risk groups by means other than simply screening for early cancer. One of the most intriguing possibilities for the appli cation of the New Biology derives from the speculation that there may be a finite number of obligatory pathways fo...

    Monoclonal antibody (MoAb) technology wiU facilitate special studies for tissue markers as an aid in diagnosis. Such studies are just beginning to be applied in practice and can be expected to achieve much wider employment as the number of tumor-specific proteins increases. The long sought single blood test diagnostic of cancer is un likely to be f...

    Rationing of health care has been under way for several years except that it has been covert. Certificate of need (CON) legislation was an attempt to ration high priced technology and new construction between hospitals. Di agnosis related group (DRG) reimbursement was an at tempt to motivate hospitals to ration care between patients in the so-calle...

    Current attempts at rationing are taking the form of third party carriers receiving targets from the Health Care Finance Administration (HCFA) or setting targets based on prices for insurance negotiated with industry. These targets are then reached by a variety of techniques: limiting reimbursements for certain Current Procedural Termi nology (CPT)...

    Health care experts await an emerging body of research into patient outcomes that is expected to provide pow erful information to evaluate the effectiveness of sur gical procedures, diagnostic tests, drugs, and doctors themselves.

    By control of medicine, I'm not referring to the current concerns of physicians about the control of the struc ture of health care organizations or payment proce dures. I'm referring to the loss of control over the sci ence of medicine when someone else knows more about the impact of physicians' work than they do. The threat is real. For example, q...

  5. Aug 31, 2020 · During the past 250 years, we have witnessed many landmark discoveries in our efforts to make progress against cancer, an affliction known to humanity for thousands of years. This timeline shows a few key milestones in the history of cancer research.

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  7. Mar 15, 1991 · Progress in cancer research in the 1980s has led to predictions of a technologic explosion in the 1990s. Yet, with this progress there has been a groundswell of protest at the rapidly escalating costs of health care.