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  2. my.clevelandclinic.org › health › drugsOpioids: What They Are, Side Effects & Disorders

    Higher dosages of opioids are associated with a higher risk of overdose and death — even relatively low dosages, like 20 to 40 MME per day, increase the risk. Dosages at or above 50 MME per day increase risks for overdose by at least two times the risk than someone would have at less than 20 MME per day.

  3. www.mayoclinic.org › what-are-opioids › faq-20381270What are opioids and why are they dangerous? - Mayo Clinic

    Aug 26, 2023 · When opioid medicines are dangerous. What makes opioid medicines effective for treating pain also can make them dangerous. At lower doses, opioids may make you feel sleepy. But higher doses can slow your breathing and heart rate, which can lead to death.

  4. www.bbc.com › news › health-43462975What are opioids and what are the risks? - BBC

    Mar 19, 2018 · At lower doses, opioids can make people feel sleepy, but higher doses of the drugs can slow your breathing and heart rate, which can lead to death. Mixing any opioid painkillers with alcohol, or...

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  6. www.healthline.com › what-are-opioidsWhat Are Opioids? Types, How They Work, Side Effects - Healthline

    Oct 5, 2022 · Opioids are powerful drugs that relieve pain. Learn their medical uses and side effects, plus factors that may increase opioid use disorder risk.

    • Emily Swaim

  7. www.apa.org › opioids-heroin-fentanylOpioids: What are these drugs and why are they dangerous

    Mar 19, 2018 · Opioids can be safe and effective for certain types of pain when prescribed and monitored carefully; however, they also come with potential risks, such as the development of physical tolerance (needing higher doses to achieve the same pain relief) and the development of opioid use disorder.

  8. newsnetwork.mayoclinic.org › discussion › what-areWhat are opioids and why are they dangerous? - Mayo Clinic ...

    May 1, 2018 · There are risks, though, when the medications are used incorrectly. How do opioid medications work? When opioid medications travel through your blood and attach to opioid receptors in your brain cells, the cells release signals that muffle your perception of pain and boost your feelings of pleasure.

  9. www.who.int › news-room › fact-sheetsOpioid overdose - World Health Organization (WHO)

    Due to their pharmacological effects, opioids can cause breathing difficulties, and opioid overdose can lead to death. Worldwide, in 2019 about 600 000 deaths were attributable to drug use. Close to 80% of these deaths are related to opioids, with about 25% of those deaths caused by opioid overdose.