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    • Doesn’t work better

      • Triple therapy in a single inhaler doesn’t work better than the same treatment given in three separate inhalers, research suggests. Convenience is the main advantage of taking the three drugs together. Easier dosing may help people stick with their treatment regimen and not miss doses.
      www.healthline.com/health/copd/triple-therapy-inhaler-for-copd-what-is-it

      Triple Therapy Inhaler for COPD: What Is It? - Healthline

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  3. www.nejm.org › doi › fullOnce-Daily Single-Inhaler Triple versus Dual Therapy in ...

    Apr 18, 2018 · Single-Inhaler Triple Therapy in Patients with COPD. 2m 3s. Triple inhaled therapy for chronic obstructive pulmonary disease (COPD) comprises an inhaled glucocorticoid, a long-acting...

    • David A. Lipson, Frank Barnhart, Noushin Brealey, Jean Brooks, Gerard J. Criner, Nicola C. Day, Mark...
    • 2018

  4. journal.chestnet.org › article › S0012-3692(22)03715Single vs Multiple Inhaler Triple Therapy in the COPD ... - CHEST

    Jul 1, 2022 · The choice of either pursuing multiple-inhaler triple therapy (MITT) vs single-inhaler triple therapy (SITT) is based on a combination of prescribers’ preferences, patients’ preferences, costs, and medical consideration such as concomitant asthma.

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  6. www.ncbi.nlm.nih.gov › pmc › articlesComparative efficacy of single-inhaler triple therapies for ...

    Aug 5, 2021 · Triple therapy in fixed-dose combinations (FDCs), i.e., combining ICS, LABA with LAMA and administrating by a single inhalation device, has appeared in recent years. This study aims to compare the efficacy of triple therapy in FDCs in treating patients with moderate to severe COPD.

    • Yixuan Jiang, Hao Hu, Siu-wai Leung, Siu-wai Leung
    • 10.1371/journal.pone.0255545
    • 2021
    • PLoS One. 2021; 16(8): e0255545.

  7. www.ncbi.nlm.nih.gov › pmc › articlesThe effects of single inhaler triple therapy vs single ...

    Jul 11, 2019 · Single inhaler triple therapy was associated with a significantly lower risk of COPD exacerbation compared with LABA/LAMA (rate ratio, 0.69; 95% confidence interval [CI] 0.55 to 0.87, I2 =85%), and ICS/LABA (rate ratio, 0.81; 95% CI 0.73 to 0.89, I2 =29%) dual therapy.

    • Chih-Cheng Lai, Cheng-Hsin Chen, Charlotte Yu Hsuan Lin, Cheng-Yi Wang, Ya-Hui Wang
    • 10.2147/COPD.S200846
    • 2019
    • 2019

  8. www.ncbi.nlm.nih.gov › pmc › articlesBeyond Dual Bronchodilation – Triple Therapy, When and Why

    Jan 14, 2022 · The effects of single inhaler triple therapy vs single inhaler dual therapy or separate triple therapy for the management of chronic obstructive pulmonary disease: a systematic review and meta-analysis of randomized controlled trials.

  9. www.healthline.com › health › copdTriple Therapy Inhaler for COPD: What Is It? - Healthline

    Mar 10, 2023 · Triple therapy combines three COPD drugs in a single inhaled dose. Read on to learn how triple therapy works, who's a good candidate, and how it compares to dual therapy.

  10. respiratory-research.biomedcentral.com › articlesSingle-inhaler triple vs single-inhaler dual therapy in ...

    Jul 23, 2021 · Single-inhaler triple therapy reduced the risk of exacerbation and prolonged the time to first exacerbation compared with single-inhaler dual therapy. The FEV1 increased significantly more under single-inhaler triple therapy than under ICS/LABA FDC (mean difference, 103.4 ml; 95% CI 64.65‐142.15).