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  1. Oct 26, 2022 · Due to the risk of addiction associated with the prolonged use of prescription opioids, there is an urgent need for non-opioid alternatives for the treatment of chronic pain.

    • Deep Shukla
  2. Feb 3, 2023 · Some opioids, such as heroin, have no medical function and are illegal to use or distribute except in medical research. This article will explain the purpose of narcotics or opioids, along...

  3. May 16, 2024 · A tranquilizer called xylazine, a non-opioid sedative, is increasingly being found in the US illegal drug supply and linked to overdose deaths. 1 Xylazine—which is not approved for use in people and can slow down the brain and breathing, make the heart beat slower, and lower blood pressure in people, is especially dangerous when combined with op...

  4. May 2, 2024 · Nonopioid treatment options for subacute and chronic pain. Nonpharmacologic pain therapies. Many noninvasive, nonpharmacologic approaches can improve pain and function without risk for serious harms. Examples of noninvasive, nonpharmacologic approaches that can be used to manage pain include:

  5. Aug 26, 2023 · When opioid medicines are dangerous. What makes opioid medicines effective for treating pain also can make them dangerous. At lower doses, opioids may make you feel sleepy. But higher doses can slow your breathing and heart rate, which can lead to death.

  6. Then, we explore the rationale and potential of novel non-opioid-based treatments that target other brain systems, including the glutamatergic, endocannabinoid, the orexigenic, and the serotonergic systems.

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  8. May 3, 2023 · The term “narcotic” is sometimes used instead of “opioid.” This can create confusion because some people use the term to refer to any illegal drug. It can also have pejorative connotations.