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      • A typical UIP pattern on HRCT has been shown to be highly accurate for the presence of a UIP pattern on surgical lung biopsy (90-100%); reliable imaging features of UIP are currently considered to be diagnostic of a UIP pattern, without the need for a surgical lung biopsy. 1 Surgical lung biopsy is currently recommended when HRCT findings are not typical of UIP, a definitive diagnosis being established by specific combinations of imaging and histopathological findings. 1 Therefore, correct...
      www.ncbi.nlm.nih.gov/pmc/articles/PMC5790657/
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  2. Jun 19, 2024 · This helps radiologists to determine the certainty of usual interstitial pneumonia (UIP) diagnosis based on HRCT chest findings. The importance of this guideline is that (definite) UIP pattern on chest HRCT precludes the need for tissue diagnosis 1,2,5 .

  3. Jun 19, 2024 · The 2018 revised diagnostic HRCT criteria for usual interstitial pneumonia (UIP) pattern published by the American Thoracic Society, the European Respiratory Society, the Japanese Respiratory Society, and the Latin American Thoracic Association has converged to a similar categorization of the HRCT findings into four groups.

  4. Jul 12, 2024 · The histological diagnosis of UIP is based on temporal and spatial heterogeneity, the identification of fibrotic lesions at different stages (fibroblastic infiltrates, mature fibrosis, and honeycombing) within the same biopsy specimen and architectural distortion.

    • How do radiologists determine Normal interstitial pneumonia (UIP) diagnosis based on HRCT?1
    • How do radiologists determine Normal interstitial pneumonia (UIP) diagnosis based on HRCT?2
    • How do radiologists determine Normal interstitial pneumonia (UIP) diagnosis based on HRCT?3
    • How do radiologists determine Normal interstitial pneumonia (UIP) diagnosis based on HRCT?4
    • How do radiologists determine Normal interstitial pneumonia (UIP) diagnosis based on HRCT?5
  5. •Terminology: Illustrate HRCT findings of lung fibrosis, and pitfalls •Accurately (and concisely) describe HRCT findings of UIP focusing on patterns •Discuss how integrating clinical and HRCT findings can obviate the need for surgical biopsy in some patients •Pearls •Review HRCT signs suggestive of CTD in patients with UIP pattern

  6. Dec 4, 2016 · Current guidelines describe three UIP patterns based on HRCT findings: a typical UIP pattern; a pattern designated “possible UIP”; and a pattern designated “inconsistent with UIP”, each pattern having important diagnostic implications.

    • Pedro Paulo Teixeira e Silva Torres, Marcelo Fouad Rabahi, Maria Auxiliadora Carmo Moreira, Gustavo ...
    • 10.1590/S1806-37562016000000368
    • 2017
    • J Bras Pneumol. 2017 Sep-Oct; 43(5): 393-398.
  7. Feb 28, 2022 · A pathologic or radiologic diagnosis of UIP is required for the clinical/multidisciplinary diagnosis of idiopathic pulmonary fibrosis (IPF) but it has also been described in several...

  8. Dec 15, 2021 · The pathologic explanation for this phenomenon is quite straightforward. Since HRCT criteria for UIP require honeycombing, radiologists do not diagnose UIP in cases where they cannot see honeycombing. Instead, they often reach for another label, which may or may not be correct.