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No conclusive data
- There are no conclusive data yet that triple therapy reduces mortality in COPD. Future, well-designed and -powered trials are needed to validate the findings on mortality.
breathe.ersjournals.com/content/19/1/220260Impact of triple therapy on mortality in COPD | European ...
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Does triple therapy reduce mortality in patients with COPD?
Does triple therapy improve chronic obstructive pulmonary disease management?
What is triple inhaled therapy for chronic obstructive pulmonary disease (COPD)?
Aug 28, 2023 · Role of triple therapy in chronic obstructive pulmonary disease (COPD) management is supported by growing evidence, but consensus is lacking on various aspects. We conducted a Delphi survey in respiratory experts on the effects of triple therapy on exacerbation reduction, early optimization, pneumonia risk, and mortality benefits in COPD ...
- 10.2147/COPD.S424128
- 2023
Jan 14, 2022 · The evidence generated by pivotal RCTs supports the use of triple therapy in patients who present for the first time and have severe airway obstruction, are symptomatic, have had frequent moderate or severe exacerbations in the previous year, and have peripheral eosinophilia.
Mar 23, 2022 · Abstract. Chronic obstructive pulmonary disease (COPD) is a complex disease which consists in the reduction of the airflow and leads to the disruption of the pulmonary tissue due to a chronic inflammation.
- 10.3389/fmed.2022.816843
- 2022
- Front Med (Lausanne). 2022; 9: 816843.
Jun 14, 2024 · The Global Initiative for Chronic Obstructive Lung Disease (GOLD) guidelines recommend triple therapy as initial treatment for ‘group E’ (consider when blood EOS ⩾ 300/µl), or as maintenance treatment for patients with frequent exacerbations, noting recent promising evidence indicating possible mortality benefits or reductions in ...
Mar 23, 2022 · Above all, many robust data are now available on the effectiveness of the triple therapy to reduce mortality in COPD patients. Keywords: CV mortality; ICS; LABA; LAMA; chronic obstructive pulmonary disease (COPD); triple inhaled therapy. Copyright © 2022 Solidoro, Albera, Ribolla, Bellocchia, Brussino and Patrucco. Publication types. Review.
Does regular pharmacological treatment including inhaled corticosteroids (ICS) reduce mortality in patients with chronic obstructive pulmonary disease (COPD)?
Nov 9, 2017 · Triple therapy is recommended by the Global initiative for Chronic Obstructive Lung Disease (GOLD) for patients who experience recurrent exacerbations despite treatment with either a dual bronchodilator (preferred initial therapy) or LABA/ICS combination (alternative initial therapy).