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      • In this study, compared to colonoscopy, FIT screening did not improve screening uptake by individuals at high risk of CRC, resulting in less detection of advanced colorectal neoplasia. Further studies are needed to assess how screening uptake could be improved in this high-risk group, including by inclusion in population-based screening programs.
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  2. May 13, 2022 · This is supported by randomized controlled trial data that found that offering patients a choice between colonoscopy or FIT (26.5%) improves screening uptake when compared to only recommending colonoscopy (17.5%; p < 0.001) (Pilonis et al., 2021).

    • 10.1016/j.pmedr.2022.101825
    • 2022/06
    • Prev Med Rep. 2022 Jun; 27: 101825.
  3. Oct 24, 2023 · The primary outcome was to compare screening uptake between colonoscopy and FIT. The secondary outcome was to determine the efficacy of each strategy to detect advanced colorectal neoplasia (adenoma or serrated polyps ≥10 mm, polyps with tubulovillous architecture, high-grade dysplasia, and/or CRC).

    • 10.1371/journal.pmed.1004298
    • 2023/10
    • PLoS Med. 2023 Oct; 20(10): e1004298.
  4. Mar 22, 2022 · The Task Force recommends screening with one of several screening strategies: high-sensitivity guaiac fecal occult blood test (HSgFOBT), fecal immunochemical test (FIT), multi-target stool DNA (mt-sDNA) test, computed tomographic (CT) colonography (virtual colonoscopy), flexible sigmoidoscopy, flexible sigmoidoscopy with FIT, or traditional ...

  5. Jun 21, 2023 · Large-scale comparative effectiveness trials comparing colonoscopy and FIT for colorectal cancer outcomes are underway, but results are not yet available. This review will separately state the “best case” for FIT and colonoscopy as the screening tool of first choice.

  6. Oct 24, 2023 · In this study, we investigated whether the uptake of FIT screening is superior to the uptake of colonoscopy screening in the familial-risk population, with an equivalent effect on CRC detection.

  7. Oct 24, 2023 · Studies conducted in FDR referred for screening suggest that fecal immunochemical testing (FIT) was not inferior to colonoscopy in terms of diagnostic yield and tumor staging, but screening uptake of FIT has not yet been tested in this population.

  8. May 3, 2022 · Key points. Throughout the world, the most used approach for colorectal cancer screening is the faecal immunochemical test (FIT). Colonoscopy is the most common screening modality in the...