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Jan 1, 2016 · Abstract. Thyroid hormone replacement has been used for more than a century to treat hypothyroidism. Natural thyroid preparations (thyroid extract, desiccated thyroid, or thyroglobulin), which contain both thyroxine (T 4) and triiodothyronine (T 3), were the first pharmacologic treatments available and dominated the market for the better part ...
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Thyroid hormone replacement has been used for more than a...
- Thyroid Hormone Replacement Therapy
Saravanan P, et al. Partial substitution of thyroxine (T 4)...
- The Treatment of Hypothyroidism by Thyroid Transplantation
The .gov means it’s official. Federal government websites...
- Controlled Clinical Trial of Combined Triiodothyronine and Thyroxine in The Treatment of Hypothyroidism
A -double-blind crossover trial of a combined preparation of...
- Clinical Remarks on Certain Changes Observed in The Urine in Myxœdema After The Administration of Glycerine Extract of Thyroid Gland
The .gov means it’s official. Federal government websites...
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Levothyroxine, also known as L-thyroxine, is a synthetic form of the thyroid hormone thyroxine (T 4). [ 5 ][ 8 ] It is used to treat thyroid hormone deficiency (hypothyroidism), including a severe form known as myxedema coma. [ 5 ] It may also be used to treat and prevent certain types of thyroid tumors. [ 5 ]
Mar 13, 2010 · It is estimated that about 3–5% of the general population has some form of hypothyroidism and symptoms of both disorders vary depending on the level of thyroxine (1) present in the blood. 2 Synthetic hormone (Thyroxine, T 4, 1) is prescribed as its sodium salt, which is commonly called ‘levothyroxine sodium,’ to supplement the deficiency of natural hormone and alleviate the symptoms in patients suffering from congenital or acquired hypothyroidism. 1, 1(a), 1(b), 1(c), 1(d), 1(e), 1(f ...
- Sanjay R. Chemburkar, Kris C. Deming, Rajarathnam E. Reddy
- 2010
Mar 12, 2021 · The therapeutic use of levothyroxine (LT4) arose from observations made in the second half of the nineteenth century that linked the severe physical and cognitive defects of cretinism with an under-developed, or absent, thyroid gland. Improved outcomes for these subjects following empirical treatment with crude thyroid extracts spurred further ...
- George J. Kahaly
- gkahaly@uni-mainz.de
- 2021
Thyroxine. Hypothyroidism is one of the most common endocrine disorders, affecting as much as 10% of the global population. There is a rich cultural milieu of treatment history and interventions dating as far back as 2 millennia. Chinese cretins were treated with sheep thyroid in the 6th century. In 1890, tran ….
- Roselyn Cristelle I. Mateo, James V. Hennessey
- 2019
Mar 1, 2011 · Thyroxine was isolated in 1915 by Kendall 30 (actually, on Christmas Day, 1914), its chemical structure determined in 1926 by Harington, 31 and it was synthesized by Harington and Barger in 1927. 32 However, it took a long time before it was synthesized on a commercial basis. At first, 3 tons of pigs' thyroids were needed to isolate just 33 grams of pure thyroxine.
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Jan 5, 2016 · This article has been corrected. The original version (PDF) is appended to this article as a Supplement. Thyroid hormone replacement has been used for more than a century to treat hypothyroidism. Natural thyroid preparations (thyroid extract, desiccated thyroid, or thyroglobulin), which contain both thyroxine (T4) and triiodothyronine (T3), were the first pharmacologic treatments available and dominated the market for the better part of the 20th century. Dosages were adjusted to resolve ...
