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Ralph Marvin Steinman (January 14, 1943 – September 30, 2011) [2] was a Canadian physician and medical researcher at Rockefeller University, who in 1973 discovered and named dendritic cells while working as a postdoctoral fellow in the laboratory of Zanvil A. Cohn, also at Rockefeller University.
Sep 30, 2011 · Ralph Steinman discovered, in 1973, a new cell type that he called the dendritic cell. In cell culture experiments he demonstrated that dendritic cells can activate T-cells, a cell type that has a key role in adaptive immunity and develops an immunologic memory against many different substances.
In 1973, Steinman and Cohn discovered dendritic cells, a previously unknown class of immune cells that constantly formed and retracted their processes. This discovery changed the field of immunology. For the next four decades, until his death in 2011, Steinman’s laboratory was at the forefront of dendritic cell research.
Steinman made his Nobel Prize-winning discovery in the early 1970s, when he identified an unusual cell type in a substance derived from the spleen of a mouse. In 1973 he named the cells dendritic cells for their branching, treelike appearance.
- Kara Rogers
Oct 26, 2011 · Ralph Steinman changed the world of immunology when he discovered dendritic cells, but it took the field a long time to recognize the importance of his discovery. The idea that a new type of...
- Michel C. Nussenzweig, Ira Mellman
- 2011
Jan 1, 2012 · When Ralph M. Steinman developed pancreatic cancer, he put his own theories about cancer and the immune system to the test. They kept him alive longer than expected—but three days short...
In 1973, Rockefeller University scientist Ralph M. Steinman identified the cell type that is almost singularly responsible for commanding the efforts of all other immune cells: the dendritic cell. For this discovery, Dr. Steinman received the 2011 Nobel Prize in Physiology or Medicine.
