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Chi-chiu LEE | Cited by 308 | of Hong Kong Hospital Authority, Hong Kong (ha) | Read 7 publications | Contact Chi-chiu LEE
- Chi-chiu Lee's research works | Hong Kong Hospital Authority ...
Chi-chiu Lee's 5 research works with 92 citations and 308...
- Chi-Chiu Lee's research works | Academia Sinica, Taipei and ...
Chi-Chiu Lee's 5 research works with 1,070 citations and...
- Chi-chiu Lee's research works | Hong Kong Hospital Authority ...
- Humanized Human (-zumab) (-umab)
- Humanization of mAbs
- Human IgG
- Authors’ contributions
- Publisher’s Note
Fig. 2 Schematic overview of antibody humanization from murine antibodies (green domains) to fully human antibodies (orange domains) and associated suffixes. a The murine monoclonal antibody. b The chimeric monoclonal antibody: variable regions are of murine origin, and the rest of the chains are of human origin. c Humanized monoclonal antibody: on...
Due to the availability, low cost and quick production time for mouse mAbs, humanization of mouse mAbs has been implemented on a large scale. Non-humanized murine mAbs have many disadvantages as treatments. For example, patients treated with mouse mAbs will produce a rapid human anti-mouse antibody (HAMA) response. HAMAs will not only hasten the cl...
Reverse transcription Isotype-specific Cloning of PCR fragments vector Electroporation into helper phage Generation (C) Antigens bind Wash and Elution Phage library Analysis of phage Phage E-coli infection and generation recovery titer amplification helper phage rescue Fig. 4 Construction and affinity selection with phage-display antibody library. ...
R-M L, Y-C H, I-J L, C-C L, H-Z T, H-JL, and H-C W wrote the manuscript. R-M L, C-C L, H-Z T, and H-C W designed and illustrated Table. R-M L, Y-C H, I-J L, C-C L, H-Z T, H-JL, and H-C W designed and illustrated figures. All authors read and approved the final manuscript.
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Chi-chiu Lee is an academic researcher from Kwai Chung Hospital. The author has contributed to research in topics: Attention deficit hyperactivity disorder & Anxiety. The author has an hindex of 8, co-authored 13 publications receiving 641 citations.
Chi-chiu Lee's 5 research works with 92 citations and 308 reads, including: Genetic Overlap Between Attention Deficit/Hyperactivity Disorder and Autism Spectrum Disorder in SHANK2 Gene.
John Lee Ka-chiu GBM SBS PDSM PMSM (Chinese: 李家超; born 7 December 1957) is a Hong Kong politician and former police officer who is the fifth and current Chief Executive of Hong Kong. Originally a police officer, Lee served as the Deputy Commissioner of the Hong Kong Police Force from 2010 to 2012.
Chi-Chiu Lee's 5 research works with 1,070 citations and 11,882 reads, including: Podocalyxin‐Like Protein 1 Regulates Pluripotency through the Cholesterol Biosynthesis Pathway
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Jan 11, 2023 · Medium-sized structural variants (SVs) are difficult to detect using SNP arrays or second generation sequencing, and may account for part of the missing heritability of SCZ. Aims and objectives: To identify SVs associated with severe chronic SCZ across the whole genome.
