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Molecular nanostructures and nanomachines group. Our research focuses on problems at the intersection of molecular self-assembly, synthetic biology, nano-electronics and photonics.
I am an experimentalist, at the moment, working on a whole bunch of different projects broadly directed towards answering following questions: “What can we control the organization of individual molecules, ions, atoms, nanoparticles or proteins, at manufacturing scale, on surfaces and volumes at atomic resolution?”.
Ashwin Gopinath, Svetlana V Boriskina, WR Premasiri, L Ziegler, BM Reinhard & Luca Dal Negro Nano letters 9 (11), 3922-3929, 2009 [PDF] Near-field excitation and near-field detection of propagating surface plasmon polaritons on Au waveguide structures
So, how can we improve the errors rates in DOP from ~1 in 100 to 1 in a billion. One possible method involves decorating the ends of the origami with polymer (maybe PEG or even just ssDNA) to sterically occlude other origami from getting close.
Large area metasurfaces. A unique class of second class of applications which might benefit from DNA origami-based fabrication are those which require vast areas of substrates to be patterned at the nanoscale, but requiring little integration and tolerant to high defect densities.
Since the original description by dicke, the field of superradiance has flourished with an abundance of theoretical and experimental results relevant for engineering light absorption, developing new classes of ultrastable light sources , quantum metrology as well as quantum computing.
Synthetic synapse: (a) Schematic showing the fabrication of the “synthetic synapse” starting with an array of transistors on top of which DNA origami are localized, followed by creation of femotoliter chambers, attachment of DNA nanopores and finally plating of the cells; (b) Cross-section view of a single synthatic synapse or ‘pixel’ with a transistor, DNA origami and nanopore interfacing with the cell at a defined distance; (c) is a cartoon of a natural electrical synapse ...
If you want to schedule a meeting with me. Figure out a time when I am not busy and send a calendar invite to my email.
This stochasticity arises because all bio-chemical reactions, at its core, is driven by random intermolecular collisions. Over the last 15 years, two forms of stochasticity and the associated `noise' has been very well characterized in biochemical networks within prokaryotes and eukaryotes.
Ashwin Gopinath. Home-Test; Home??? Publications; Calendar; Blog/Fun; Accessibility
