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  1. Part 1. The Government of India has decided to introduce pentavalent vaccine in the national immunization programme in selected states. Pentavalent vaccine provides protection to a child from 5 life-threatening diseasesDiphtheria, Pertussis, Tetanus, Hepatitis B and Hib.

  2. A pentavalent vaccine combines five vaccines into one dose. Pentavalent vaccines include: DTwP-HepB-Hib vaccine, used by UNICEF in low/middle income countries. DTaP-IPV/Hib vaccine, used in the UK until 2017 (replaced by a hexavalent vaccine) DTaP-IPV-HepB vaccine, approved in the US.

  3. Global pentavalent vaccines are variations of the UK’s 5-in-1 vaccine, and recommended as part of routine childhood immunisations by the World Health Organization (WHO). The vaccines give protection against five diseases - diphtheria, tetanus, pertussis, hepatitis B, and Hib disease (Haemophilus influenzae type b) (DTwP-HepBHib).

  4. Pentavalent vaccine has been introduced in 8 States/UTs i.e. Tamil Nadu, Kerala, Haryana, J&K, Gujarat, Karnataka, Goa and Puducherry. Pentavalent vaccine expansion is planned in 12 States/UTs i.e. Andhra Pradesh, Telangana, Assam, Bihar, Chhattisgarh, Jharkhand, Madhya Pradesh, Punjab, Rajasthan, West

  5. Pentavalent vaccines provide great public health benefits that accrue from the ability to protect against 5 major threats to health in a single injection. Currently, pentavalent vaccines from 5 different manufacturers re prequalified by WHO and considered to be safe, effective and of assured quality.

  6. Apr 18, 2024 · Starting 1 December 2023, countries eligible for Gavi support can apply to switch to a whole-cell pertussis (wP) hexavalent vaccine – a six-in-one vaccine that combines the pentavalent antigens with inactivated polio vaccine (IPV) – or continue using pentavalent and IPV standalone vaccines.

  7. Pentavalent vaccine: Pentavalent vaccine contains five antigens i.e. Hepatitis B, Diphtheria+Pertussis+Tetanus (DPT – current trivalent vaccine) and Haemophilus influenza b (Hib) vaccine. Pentavalent vaccination is provided to the children at the age of 6, 10 and 14 weeks as primary dose.

  8. Sep 1, 2012 · Advent of combination vaccines has facilitated incorporation of additional vaccines into immunization schedule. Pentavalent vaccine, against five killer diseases–diphtheria, pertussis, tetanus, hepatitis B and Hemophilus influenza type B (Hib), has been introduced in almost all GAVI eligible countries by 2011.

  9. Oct 20, 2023 · PENBRAYA reduces the total number of doses needed for individuals to be fully vaccinated against the five most common serogroups, thereby streamlining the standard of care and potentially increasing the number of adolescents and young adults vaccinated.

  10. Dosage and vaccination schedule. Neonate: 3 doses 4 weeks apart, preferably before the age of 6 months. It is recommended to administer the 1 st dose at 6 weeks of age, the 2 nd dose at 10 weeks of age and the 3 rd dose at 14 weeks of age.

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