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Jun 26, 2018 · Apparently most pathogenic microorganisms have the capability of developing resistance to at least some antimicrobial agents. The main mechanisms of resistance are: limiting uptake of a drug, modification of a drug target, inactivation of a drug, and active efflux of a drug.
In this chapter, we will describe in detail the major mechanisms of antibiotic resistance encountered in clinical practice providing specific examples in relevant bacterial pathogens.
Nov 21, 2022 · Understanding the molecular mechanisms that bacteria use to resist the action of antimicrobials is critical to recognize global patterns of resistance and to improve the use of current...
Jul 2, 2024 · antibiotic resistance, loss of susceptibility of bacteria to the killing (bacteriocidal) or growth-inhibiting (bacteriostatic) properties of an antibiotic agent. When a resistant strain of bacteria is the dominant strain in an infection, the infection may be untreatable and life-threatening.
Jun 1, 2024 · Resistant drug uptake, target site change, efflux pump mechanism, and target site mutation are examples of resistance mechanisms. The presence of resistant bacteria and antibiotic residues in the environment requires urgent global action to combat antimicrobial resistance (AMR).
Antimicrobial Resistance (AMR) occurs when bacteria, viruses, fungi and parasites change over time and no longer respond to medicines making infections harder to treat and increasing the risk of disease spread, severe illness and death.
Dec 1, 2014 · 215 Altmetric. Metrics. Key Points. Antibiotic resistance is a global health emergency. Resistance mechanisms exist for all current antibiotics, and few new drugs are in development....
