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The Perkin reaction is an organic reaction developed by English chemist William Henry Perkin that is used to make cinnamic acids. It gives an α,β-unsaturated aromatic acid or α-substituted β-aryl acrylic acid by the aldol condensation of an aromatic aldehyde and an acid anhydride, in the presence of an alkali salt of the acid.
Perkin’s reaction mechanism includes the reaction between aromatic aldehydes, the aliphatic acid anhydride, and the alkali salt of the acid to give cinnamic acid derivatives. The Perkin reaction is an organic chemical reaction named after its discoverer – William Henry Perkin.
The Perkin reaction, also known as Perkin condensation, is an organic reaction which is used for the synthesis of α,β-unsaturated aromatic acid by the condensation of an aromatic aldehyde and an acid anhydride, in the presence of an alkali salt of the acid acting as a weak base.
Jan 28, 2022 · Perkin condensation reaction is the condensation reaction of an aromatic aldehyde and an aliphatic acid anhydride containing at least two α-hydrogen atoms in the presence of a sodium or potassium salt of the corresponding acid to form, α, β-unsaturated acid.
Jan 23, 2023 · The Perkin reaction is an organic reaction developed by William Henry Perkin that is used to make cinnamic acids. It gives an α,β-unsaturated aromatic acid by the aldol condensation of an aromatic aldehyde and an acid anhydride, in the presence of an alkali salt of the acid.
Jul 22, 2020 · It is a condensation reaction between an aromatic aldehyde with an aliphatic anhydride in presence of weak base. The mechanism involves intramolecular acyl transfer step, E2 elimination...
The Perkin reaction is an organic reaction developed by English chemist William Henry Perkin that is used to make cinnamic acids. It gives an α,β-unsaturated aromatic acid by the aldol...
In 1868, W. H. Perkin described a synthesis of coumarin by heating the sodium salt of salicyaldehyde with acetic acid. Further study led to a new discovery for preparing cinnamic acid and its analogs by means of a synthesis of very general application, which became know as the Perkin reaction.
Jul 27, 2022 · The Perkin reaction is a well-established organic reaction that produces α,β-unsaturated aromatic acids by condensing an aromatic aldehyde with an aliphatic acid anhydride in the presence of a weak base.
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