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UniProt is the world’s leading high-quality, comprehensive and freely accessible resource of protein sequence and functional information. Cite UniProt. Vitamin K beyond coagulation | Cross-references to EMDB | Cross-references to JaponicusDB | Changes to the controlled vocabulary...
The UniProt Knowledgebase (UniProtKB) is the central hub for the collection of functional information on proteins, with accurate, consistent and rich annotation.
UniProt is a freely accessible database of protein sequence and functional information, many entries being derived from genome sequencing projects. It contains a large amount of information about the biological function of proteins derived from the research literature.
UniProt is comprised of four components, each optimised for different uses: 1) The UniProt Knowledgebase (UniProtKB) is the central access point for extensive curated protein information, including function, classification, and cross-reference. UniProtKB comprises two sections:
UniProtKB/Swiss-Prot is the expertly curated component of UniProtKB (produced by the UniProt consortium). It contains hundreds of thousands of protein descriptions, including function, domain structure, subcellular location, post-translational modifications and functionally characterized variants.
The UniProt Archive (UniParc) contains all protein sequences from the main publicly available protein sequence databases. This makes UniParc the most comprehensive publicly accessible non-redundant protein sequence database. A complete list of the source databases is available on the UniProt website.
The UniProt Knowledgebase (UniProtKB), the centrepiece of the UniProt Consortium’s activities, is an expertly and richly curated protein database, consisting of two sections called UniProtKB/Swiss-Prot and UniProtKB/TrEMBL.
The Universal Protein Resource (UniProt) is a comprehensive resource for protein sequence and annotation data. The UniProt databases are the UniProt Knowledgebase (UniProtKB), the UniProt Reference Clusters (UniRef), and the UniProt Archive (UniParc).
Select a mapping of UniProt to PDB entries using the UniProt cross-references to the PDB databasePREFIX rdfs: <http://www.w3.org/2000/01/rdf-schema#> PREFIX up: <http://purl.uniprot.org/core/> SELECT ?protein ?db WHERE { ?protein a up:Protein . ?protein rdfs:seeAlso ?db . ?db up:database <http://purl.uniprot.org/database/PDB> }
There are three UniProt databases: In this tutorial we will only focus on UniProtKB. For more information on UniRef or UniParc, visit the UniProt Quick Tour. UniProtKB is the central hub for the collection of functional information on proteins, with accurate, consistent and rich annotation. It consists of two sections:
