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  1. The OECD Guidelines for the Testing of Chemicals are split into five sections: Section 1: Physical Chemical Properties. Section 2: Effects on Biotic Systems. Section 3: Environmental Fate and Behaviour. Section 4: Health Effects. Section 5: Other Test Guidelines. Access the Test Guidelines. New, updated and corrected Test Guidelines.

  2. www.oecd-ilibrary.org › environment › oecd-guidelines-for-the-testing-of-chemicalsOECD Guidelines for the Testing of Chemicals

    The OECD Guidelines for the Testing of Chemicals are a unique tool for assessing the potential effects of chemicals on human health and the environment. They are split into five sections: Section 1: Physical-Chemical properties; Section 2: Effects on...

  3. OECD Guidelines for the Testing of Chemicals are periodically reviewed in the light of scientific progress or changing assessment practices. The original Guideline 423 was adopted in March 1996 as the second alternative to the conventional acute toxicity test, described in Test Guideline 401.

  4. Apr 17, 2018 · Several important OECD guidelines are mentioned, including those for acute oral toxicity, repeated dose oral toxicity studies. The principles and procedures of acute oral toxicity testing and 28-day repeated oral toxicity studies in rodents (OECD Guideline 407) are described in detail.

  5. This Test Guideline is designed to be used in the testing of a broad range of chemicals, including pesticides and industrial chemicals. The majority of chronic toxicity studies are carried out in rodent species, and this Test Guideline is intended therefore to apply primarily to studies carried out in these species.

  6. OECD Guidelines for the Testing of Chemicals (OECD TG) are a set of internationally accepted specifications for the testing of chemicals decided on by the Organisation for Economic Co-operation and Development (OECD). They were first published in 1981.

  7. The OECD Guidelines for the Testing of Chemicals is a collection of about 150 of the most relevant internationally agreed testing methods used by government, industry and independent laboratories to identify and characterise potential hazards of chemicals.

  8. In October 2011, an OECD Expert Meeting on Inhalation Toxicity Testing was held to discuss potential revisions needed on the OECD Test Guidelines on inhalation: TGs 403 (Acute Inhalation), 436 (Acute Inhalation – Acute Toxic Class), 412 (Subacute Inhalation

  9. The first draft proposal for an OECD guidance document on the aquatic toxicity testing of difficult substances and mixtures was prepared following a meeting of the Expert Panel on the 2 nd and 3 rd of April 1998 in Paris, France.

  10. Its objective is to assist users of the TGs to select the most appropriate methodology to assess the chronic toxicity and carcinogenicity of a test chemical so that particular data requirements can be met while reducing animal usage if possible/appropriate.

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