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Learn about malaria, a mosquito-borne disease caused by various species of Plasmodium parasites. See a diagram of the life cycle of malarial parasite in humans and mosquitoes, and how to prevent and treat the infection.
Learn how Plasmodium parasites infect humans and mosquitoes, and how they reproduce and cause malaria symptoms. See an animated slide or a static infographic of the malaria parasite lifecycle stages.
- Malaria and Plasmodium Biology
- Clinical Features of Disease and Pathogenesis
- References
- Further Reading
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All Plasmodium species share a similar life cycle of two parts: 1. Parasite infection of a vertebrate host 2. Transmission of malaria from the infected vertebrae hosts to another by an insect factor The Plasmodiumlife cycle begins when sporozoites, produced in the factor, enter the blood of the vertebrate host after being bitten by a mosquito. Spor...
Malaria infection in a naive individual almost always produces a febrile (showing the symptoms of a fever) illness. The symptoms that accompany malaria are not specific and include headache, nausea, muscle pain, and rigors. Symptoms will go into remission after a few days if the patient is treated with appropriate drugs. In the case of the falcipar...
Venugopal K, Hentzschel F, Valkiūnas G, et al. (2020) Plasmodium asexual growth and sexual development in the hematopoietic niche of the host. Nat Rev Microbiol. Mar;18(3):177-189. doi: 10.1038/s41...Meibalan E, Marti M. (2017) Biology of Malaria Transmission. Cold Spring Harb Perspect Med. doi:10.1101/cshperspect.a025452.Cowman AF, Healer J, Marapana D, et al (2016) Malaria: Biology and Disease. Cell. doi:10.1016/j.cell.2016.07.055.Milner DA Jr. (2018) Malaria Pathogenesis. Cold Spring Harb Perspect Med. doi:10.1101/cshperspect.a025569.Learn how Plasmodium parasites infect humans and mosquitoes, and how they cause malaria symptoms and complications. Find out how a new vaccine can help prevent malaria in children in sub-Saharan Africa and other regions.
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Jan 7, 2021 · Life cycle of Plasmodium. All Plasmodium species share a similar life cycle [31]. It has two parts—in the first, the parasite infects a person (or a vertebrate host), and in the second, it is transmitted from the malaria patient (or infected vertebrate host) to another host by an insect vector.
- Shigeharu Sato
- 2021
Learn how malaria parasites of the genus Plasmodium infect humans and mosquitoes, and undergo asexual and sexual multiplication. Find out the geographic distribution, clinical presentation, and treatment of different malaria species.
Jun 4, 2024 · Diagram of the malaria lifecycle, including mosquito, human liver, and human blood stages. The diagram also illustrates infective vs diagnostic stages of the parasite's lifecycle. Also included are the temporal views of both p. falciparum and p. vivax.
Learn about the complex life cycle of malaria parasites and how NIAID supports basic research to understand their biology, transmission, and interaction with the human immune system. Explore topics such as parasite genomics, vector biology, disease pathogenesis, and epidemiology.
