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Har Gobind Khorana (9 January 1922 – 9 November 2011) was an Indian-American biochemist. [1] While on the faculty of the University of Wisconsin–Madison , he shared the 1968 Nobel Prize for Physiology or Medicine with Marshall W. Nirenberg and Robert W. Holley for research that showed the order of nucleotides in nucleic acids , which carry ...
Apr 5, 2022 · Because DCC also allowed a researcher to string together DNA sequences, Khorana proposed a startlingly ambitious project – the creation of an artificial gene. Nothing of this sort had ever been...
May 2, 2018 · Throughout his career, Har Gobind Khorana was devoted to working in the lab himself. When his lab undertook a new research direction, he insisted on knowing how to master the relevant experimental methods with his own hands.
Nov 5, 2024 · Har Gobind Khorana, Indian-born American biochemist who shared the 1968 Nobel Prize for Physiology or Medicine for research that helped to show how the nucleotides in nucleic acids, which carry the genetic code of the cell, control the cell’s synthesis of proteins.
Jul 7, 2004 · Har Gobind Khorana, at the University of Wisconsin, devised precise and intricate biochemical methods to produce well-defined nucleic acids, long strands of RNA with every nucleotide in exact position. The first one he made was a strand repeating the two nucleotides UCUCUC.
By the early 1950’s it was, there-fore, clear that genes are nucleic acids and that nucleic acids direct protein synthesis, the direct involvement of RNA in this process being suggested by the early work of Caspersson7 and of Brachet8.
Understanding and fighting one of the gravest enemies of humanity — The coronavirus pandemic — could not have been the same had it not been the pioneering work of Professor HarGobind Khorana, who demonstrated the role of nucleotides in protein synthesis and helped crack the genetic code.
Nov 9, 2011 · Har Gobind Khorana made important contributions to this field by building different RNA chains with the help of enzymes. Using these enzymes, he was able to produce proteins. The amino acid sequences of these proteins then solved the rest of the puzzle.
Dec 14, 2011 · Har Gobind Khorana, who died on 9 November 2011 at the age of 89, was a pioneer and a visionary. That someone with such a humble background could rise to become an icon of molecular biology...
Energized by the Nirenberg and Matthaei experiment from 1961, where a cell-free extract produced a protein made entirely of phenylalanine when poly-U was added, Gobind's group at the Institute for Enzyme Research at the University of Wisconsin–Madison worked around the clock in double shifts to synthesize all of the possible triplet tri-nucleoti...
