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  1. Jul 7, 2022 · Bubonic plague can advance and spread to the lungs, which is the more severe type of plague called pneumonic plague. Pneumonic plague, or lung-based plague, is the most virulent form of plague. Incubation can be as short as 24 hours. Any person with pneumonic plague may transmit the disease via droplets to other humans. Untreated pneumonic ...

  2. Plague. Plague is an infectious disease caused by Yersinia pestis bacteria, usually found in small mammals and their fleas. The disease is transmitted between animals via their fleas and, as it is a zoonotic bacterium, it can also transmit from animals to humans. Humans can be contaminated by the bite of infected fleas, through direct contact ...

  3. Oct 23, 2017 · Plague is an infectious disease found in some small mammals and their fleas. People can contract plague if they are in bitten by infected fleas, and develop the bubonic form of plague. Sometimes bubonic plague progresses to pneumonic plague, when the bacteria reaches the lungs. Person-to-person transmission is possible through the inhalation of ...

  4. Oct 1, 2021 · Plague is endemic in Madagascar and cases are reported each year in bubonic and pneumonic forms. The favorable season for transmission of the disease generally lasts from September to April. Cases are usually reported from the central highlands of the country, located at an altitude of over 700 meters, as is the situation with the current outbreak involving the regions of Itasy and Haute Matsiatra.

  5. Jul 23, 2020 · Bubonic plague is the most common form of plague and is caused by the bite of an infected flea. The plague bacillus, Y. pestis, enters at the bite site and travels through the lymphatic system to the nearest lymph node where it replicates. At advanced stages of the infection, the inflamed lymph nodes can turn into suppurating open sores.

  6. Nov 27, 2017 · From the 1 August through 22 November 2017, a total of 2348 confirmed, probable and suspected cases of plague, including 202 deaths (case fatality rate 8.6 %), were reported by the Ministry of Health of Madagascar to WHO. There were 1791 cases of pneumonic plague, of which 22% were confirmed, 34% were probable, and 44% were suspected.

  7. Oct 8, 2017 · Plague is an endemic disease in Madagascar, with cases of bubonic plague being reported nearly every year, particularly during the epidemic season between September and April. However, the ongoing pneumonic plague remains an unusual and serious event, particularly since it is occurring in densely populated coastal cities.

  8. Nov 2, 2017 · From 1 August through 30 October 2017, a total of 1801 confirmed, probable and suspected cases of plague, including 127 deaths, have been reported by the Ministry of Health of Madagascar to WHO. Of these, 1111 (62%) were clinically classified as pneumonic plague, including 257 (23%) confirmed, 374 (34%) probable and 480 (43%) suspected cases.

  9. Nov 1, 2015 · In 2003 the Institut Pasteur, Madagascar developed a rapid diagnostic test for both pneumonic and bubonic plague antigens that was pilot tested by health workers in 26 sites in Madagascar. The tests were highly successful - results appeared after 15 minutes instead of the usual 15 days; the test was sensitive, reliable and easily to use at the patient's bedside.

  10. Oct 12, 2023 · Global consultation on Plague Vaccines. 12 October 2023 13:00 – 18:00 CET. Webinar. The WHO R&D Blueprint team for Epidemics is organizing a global consultation to discuss Plague: What R&D progress has been achieved and how can we accelerate the development of a vaccine? scheduled for 12 October 2023 (13:00 – 18:00 CET) During this ...

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