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  1. Jan 12, 2023 · Visceral leishmaniasis (VL), also known as kala-azar, is fatal if left untreated in over 95% of cases. It is characterized by irregular bouts of fever, weight loss, enlargement of the spleen and liver, and anaemia. Most cases occur in Brazil, east Africa and India. An estimated 50 000 to 90 000 new cases of VL occur worldwide annually, with ...

  2. Post-kala-azar dermal leishmaniasis. A complication of kala-azar, is mainly seen in East Africa and South-East Asia, including India. It is characterized by discoloured (hypopigmented) flat skin (macular) rash, combined with some slightly elevated (maculopapular) or elevated (nodular) rash, usually in patients who have recovered from the disease.

  3. May 22, 2020 · VL, or kala-azar, is the most severe form of leishmaniasis. The main signs are prolonged irregular bouts of fever, enlarged spleen and/or loss of weight. Other signs and symptoms include anaemia, enlarged liver, cough, diarrhoea and enlarged lymph nodes.

  4. Jul 29, 2021 · Kala-azar remains one of the top parasitic diseases for outbreak and mortality potential. In 2019, more than 90% of new cases reported to WHO occurred in 10 countries: Brazil, Eritrea, Ethiopia, India, Iraq, Kenya, Nepal, Somalia, South Sudan and Sudan.Poverty is an increased risk factor as is poor housing and domestic sanitary conditions (such as a lack of waste management or open sewerage).

  5. PKDL (post-kala-azar dermal leishmaniasis), a complication of VL, is mainly seen in East Africa and South-East Asia. It is characterized by a discoloured (hypopigmented) flat skin (macular) rash, combined with some slightly elevated (maculopapular) or elevated (nodular) rash, usually in patients who have recovered from VL.

  6. Oct 31, 2023 · Kala-azar leads to symptoms such as fever, weight loss, spleen and liver enlargement, and, if left untreated, can prove fatal in over 95% of cases. Bangladesh was successfully validated by WHO based on the fact that the number of reported cases of visceral leishmaniasis was below 1 per 10 000 population in each of the country’s subdistricts for at least 3 consecutive years.

  7. Jul 2, 2021 · Visceral leishmaniasis is commonly known as kala-azar (KA), a word coined in the late nineteenth century in India, which literally means “black disease”, referring to the greyish or blackish discolouration of the skin during infection, from the Hindi word for black (kala) and the Persian word for disease (azar). The disease is caused by the parasite L. donovani and it remains one of the major eco-epidemiological hotspots of the world. The earliest cases of KA in India can be traced back ...

  8. Apr 23, 2024 · Also known as kala-azar, visceral leishmaniasis is the world’s deadliest parasitic killer after malaria. It causes fever, weight loss, spleen and liver enlargement, and, if not treated, death. Kala-azar is transmitted by the bite of infected sandflies and is endemic in 80 countries , mainly in Eastern Africa, South Asia, and Latin America.

  9. Aug 3, 2022 · In the current national strategic plan, National Kala-azar Elimination Programme (NKEP) has set a target of achieving zero transmission of Kala-azar by 2025. Vector control is one of the important strategies of NKEP for interruption of transmission of Kala-azar in Bangladesh. Bangladesh achieved the target for elimination of Kala-azar as a public health problem, with the annual incidence of Kala-azar cases below one case per 10,000 population at all endemic Upazilas in 2016. Communicable ...

  10. May 29, 2019 · “ Nepal is the second country in the region to roll out case-based surveillance for kala-azar, and the country’s commitment and dedication of local staff to implementation is exemplary, ” said Dr Lise Grout, Epidemiologist, WHO Department of Control of Neglected Tropical Diseases. WHO supported national efforts to design, field test and pilot the surveillance system.

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