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Congenital rubella syndrome (CRS) occurs when a human fetus is infected with the rubella virus (German measles) via maternal-fetal transmission and develops birth defects. [1] The most common congenital defects affect the ophthalmologic, cardiac, auditory, and neurologic systems.
Aug 8, 2023 · However, maternal infection during the first trimester of pregnancy can cause a fetal malformation syndrome called congenital rubella syndrome. Rubella, also known as German Measles, is a viral illness characterized by maculopapular rash, lymphadenopathy, and fever.
Congenital rubella syndrome (CRS) affects newborns and can cause several health problems, like congenital heart disease and intellectual disability. It can affect your baby if you get rubella during pregnancy. CRS is preventable with rubella vaccination before pregnancy.
May 14, 2024 · Rubella is the leading vaccine-preventable cause of birth defects, accounting for an estimated 100 000 infants born with congenital rubella syndrome (CRS) each year worldwide. Rubella virus infection during pregnancy may result in miscarriage, fetal death or CRS.
Keywords: Rubella, infection, congenital rubella syndrome, CRS, autism spectrum disorder, vitamin A, retinoids, liver, pregnancy, vaccinations. 1. Introduction. Rubella is a member of the togaviridae family, usually causing a benign systemic illness resembling a mild case of measles, and previously known as ‘germane’ (hence, ‘German’) measles . The infection is characterized by rash, fever and lymphadenopathy.
Congenital rubella syndrome is caused by a virus known as a rubivirus. When adults and children contract the disease, it is known as rubella, or German measles. If a pregnant woman contracts rubella during her first trimester, there is a very good chance that she will pass it on to her fetus.
Sep 30, 2024 · Rubella is a leading cause of vaccine-preventable birth defects. When a woman is infected with the rubella virus during pregnancy, particularly in the first trimester, the newborn can have birth defects, known as congenital rubella syndrome (CRS).
Dec 4, 2023 · If a woman gets rubella shortly before getting pregnant or during the first three months of pregnancy, it is very likely to result in miscarriage or congenital anomalies known as congenital rubella syndrome (CRS).
Apr 22, 2024 · Rubella is very dangerous for developing babies and can cause congenital rubella syndrome (CRS). Anyone who is not vaccinated against rubella is at risk of getting the disease. You should make sure you are vaccinated against rubella before you get pregnant.
May 11, 2022 · Up to 90% of infants born to mothers who had rubella during the first 12 weeks of pregnancy develop congenital rubella syndrome. This syndrome can cause one or more problems, including: Growth delays
