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Jun 18, 2024 · Professor Siddharthan Chandran is Director of Centre for Clinical Brain Sciences, Edinburgh Neuroscience, Euan MacDonald Centre and Anne Rowling Regenerative Neurology Clinic at the University of Edinburgh.
- Stem Cell Biology & Regenerative Neurology
The Chandran lab has developed protocols for the conversion...
- Edinburgh Neuroscience
Home to one of the largest neuroscience groupings in Europe,...
- Centre for Discovery Brain Sciences
Centre for Discovery Brain Sciences (CDBS) is an...
- Stem Cell Biology & Regenerative Neurology
Professor Siddharthan Chandran works in the emerging discipline of Regenerative Neurology. His research combines laboratory activity that includes human stem cells with specialist clinics (multiple sclerosis [MS] and motor neurone disease [MND]) to both study disease as well as undertake early-phase clinical trials.
Jun 14, 2023 · Professor Siddharthan Chandran, a world-leading expert in neurodegenerative diseases, will become the new Director of the UK Dementia Research Institute (UK DRI), based at UCL, from 1 October 2023.
- At A Glance
- Scientific Goals
- Team Members
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- Key Publications
Dissecting a genetic cause of amyotrophic lateral sclerosis (ALS) and frontotemporal dementia (FTD) Amyotrophic lateral sclerosis (ALS, also known as motor neurone disease (MND)) and frontotemporal dementia (FTD) are neurodegenerative diseases, which emerging evidence shows may have significant overlap in biological cause. Although most people who ...
The overall objective of this UK DRI programme, led by Prof Siddharthan Chandran, is to better understand glial-neuronal cross talk and how this is altered in neurodegenerative disorders, using patient-derived mutant C9orf72iPS cell lines as a prototypic example, and determining whether manipulating axo-glial interaction is neuroprotective. The C9o...
Dr Karen Burr (Project Officer) Dr David Hampton (Academic) Dr Poulomi Banerjee (Postdoctoral Researcher) Dr Roderick Carter (Postdoctoral Researcher) Dr Marcus Keatinge (Postdoctoral Researcher) Dr Vidya Ramesh (Postdoctoral Researcher) Dr Arpan Mehta (Postdoctoral Researcher) Dr Nhan Pham (Postdoctoral Researcher) Dr Paul Baxter (Postdoctoral Res...
Within UK DRI: 1. Prof Giles Hardingham, UK DRI at Edinburgh 2. Prof Chris Shaw, UK DRI at King's 3. Prof Tara Spires-Jones, UK DRI at Edinburgh 4. Prof Dario Alessi, UK DRI Associate Member, MRC PPU, University of Dundee 5. Prof Josef Priller, UK DRI at Edinburgh 6. Prof Adrian Isaacs UK DRI at UCL Beyond UK DRI: 1. Prof Colin Smith, University of...
C9orf72 gene, frontotemporal dementia (FTD), amyotrophic lateral sclerosis (ALS), triplet repeat expansions, glial cells
Banerjee P, Mehta AR, Nirujogi RS, Cooper J, James OG, Nanda J, Longden J, Burr K, McDade K, Salzinger A, Paza E, Newton J, Story D, Pal S, Smith C, Alessi DR, Selvaraj BT, Priller J, Chandran S. Cell-autonomous immune dysfunction driven by disrupted autophagy in C9orf72-ALS iPSC-derived microglia contributes to neurodegeneration. Sci Adv. 2023 Apr...
Professor Siddharthan Chandran is Director of the UK Dementia Research Institute (UK DRI) and an expert in neurodegenerative diseases. He is a practising neurologist and scientist working at the forefront of the emerging discipline of regenerative neurology, renowned for his work in MND and MS.
Jan 1, 2009 · Professor Siddharthan Chandran is Director of the UK Dementia Research Institute, and an internationally leading expert in neurodegenerative diseases.
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Jun 14, 2023 · We are delighted to announce that Prof Siddharthan Chandran, a world-leading expert in neurodegenerative diseases, will become the new Director of UK DRI from 1 October 2023. Prof Chandran is a clinician-scientist at the forefront of the emerging discipline of Regenerative Neurology.
