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The importance of this guideline is that (definite) UIP pattern on chest HRCT precludes the need for tissue diagnosis 1,2,5. However, unfortunately up to 20% of inconsistent with UIP group (or actually atypical UIP) can be UIP on biopsy or progress clinically to a diagnosis of idiopathic pulmonary fibrosis (IPF).
Jul 12, 2024 · UIP pattern at CT has specific diagnostic criteria on HRCT 16 which include honeycombing, traction bronchiectasis and traction bronchiolectasis. The distribution is often widespread, asymmetric, and heterogeneous but with subpleural and basal predominance 23 .
Jun 19, 2024 · the presence of this pattern, in the correct clinical setting, permits a confident diagnosis of IPF (idiopathic pulmonary fibrosis) if the clinical setting is equivocal for IPF, lung biopsy and further review in a multidisciplinary meeting are recommended Probable UIP CT pattern. distribution heterogenous basal. subpleural predominance. features
May 23, 2024 · Non-specific interstitial pneumonia (NSIP) is the second most common morphological and pathological pattern of interstitial lung diseases after UIP. NSIP is commonly associated with connective tissue disease (CTD) and the underlying diagnosis and management are best decided by a multidisciplinary team.
Nodular pulmonary ossification may be seen in fibrotic areas. The positive predictive value of CT in the diagnosis of UIP is high and ranges from 70 to 100% 1. Similar to the pathology specimen, cross-sectional imaging also reveals heterogeneity, with patchy areas of fibrosis alternating with areas of normal lung 5.
The webpage provides updated diagnostic HRCT criteria for usual interstitial pneumonia (UIP) pattern based on literature review and expert opinion of the Fleischner Society.
Case Discussion. These findings are consistent with UIP pattern. UIP has distinctive HRCT findings. If the UIP pattern is of unknown cause (i.e. idiopathic), the disease is called idiopathic pulmonary fibrosis (IPF).
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May 22, 2024 · More than 200 different antigens have been associated with the development of hypersensitivity pneumonitis. Antigen exposure may be domestic, industrial and/or recreational and there may be more than one antigen exposure 14: microbes. fungi/molds, e.g. mushrooms, Aspergillus, Cryptococcus. yeasts, e.g. candida.
Oct 8, 2024 · Honeycombing describes small adjacent subpleural cystic structures in the context of established pulmonary fibrosis with destruction of lung architecture and traction bronchiolectasis. A single layer of cysts is now considered sufficient to apply this descriptor in the correct context 11. Terminology. The terms microcystic honeycombing and ...