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      • DNA replication starts at a single origin of replication, and the two replication forks that form there move in opposite directions (at around 500–1000 nucleotides per second) until they meet halfway around the chromosome. E. coli can only contribute to DNA replication at the initiation stage.
      unacademy.com/content/csir-ugc/study-material/life-sciences/relationship-between-replication-origin-and-replication-fork/

      Relationship Between Replication Origin and Replication Fork

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  3. www.ncbi.nlm.nih.gov › pmc › articlesThe Replication Fork: Understanding the Eukaryotic Replication...

    Jan 29, 2013 · Eukaryotic cells must accurately and efficiently duplicate their genomes during each round of the cell cycle. Multiple linear chromosomes, an abundance of regulatory elements, and chromosome packaging are all challenges that the eukaryotic DNA replication machinery must successfully overcome.

    • Adam R. Leman, Eishi Noguchi
    • 10.3390/genes4010001
    • 2013
    • Genes (Basel). 2013 Mar; 4(1): 1-32.

  4. en.wikipedia.org › wiki › Origin_of_replicationOrigin of replication - Wikipedia

    Replication proceeds bidirectionally from origins and terminates when replication forks from adjacent active origins meet (iv). The origin of replication (also called the replication origin) is a particular sequence in a genome at which replication is initiated. [1]

  5. bio.libretexts.org › Bookshelves › Introductory_and14.3C: DNA Replication in Eukaryotes - Biology LibreTexts

    Oct 31, 2023 · During initiation, proteins bind to the origin of replication while helicase unwinds the DNA helix and two replication forks are formed at the origin of replication. During elongation, a primer sequence is added with complementary RNA nucleotides, which are then replaced by DNA nucleotides.

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  7. bio.libretexts.org › Bookshelves › Introductory_and9.2: DNA Replication - Biology LibreTexts

    Mar 17, 2022 · Replication in eukaryotes starts at multiple origins of replication, while replication in prokaryotes starts from a single origin of replication. The DNA is opened with enzymes, resulting in the formation of the replication fork.

  8. www.nature.com › scitable › topicpageReplication Fork, Fork Protection Complex | Learn Science at ...

    DNA replication occurs during the synthesis (S) phase of the cell cycle and starts at predefined DNA sequences known as replication origins; this start is also known as origin firing (Errico &...

  9. bio.libretexts.org › Courses › City_College_of_SanSection 7.5: DNA Replication in Prokaryotes - Biology LibreTexts

    Sep 22, 2024 · Once the chromosome has been completely replicated, the two DNA copies move into two different cells during cell division. The process of DNA replication can be summarized as follows: DNA unwinds at the origin of replication. Helicase opens up the DNA-forming replication forks; these are extended bidirectionally.

  10. www.ncbi.nlm.nih.gov › pmc › articlesOrigins of DNA replication - PMC - National Center for ...

    Sep 12, 2019 · Despite the fundamental nature of these events, organisms have evolved surprisingly divergent strategies that control replication onset. Here, we discuss commonalities and differences in replication origin organization and recognition in the three domains of life.