Search results
- “The immune system must be able to differentiate between its defence function and its cleaning function,” says Professor Karlsson. “When it can’t, there’s a risk of autoimmune disease when signals linked to the clearing function over-activate the immune system so much that its starts to attack endogenous cells.”
news.ki.se/the-interaction-between-b-cells-and-macrophagesThe interaction between B cells and macrophages | Karolinska ...
May 3, 2024 · Inflammatory responses in cancer and autoimmunity – Mikael Karlsson's Group. Autoinflammation is part of several types of diseases. It drives auto-reactive B cells that contribute to autoimmune disease and create an environment in which tumors are allowed to grow.
- Mikael Karlsson Group - Research focus | Karolinska Institutet
Our research focuses on B Cells and Autoinflammation with a...
- Mikael Karlsson Group - Research focus | Karolinska Institutet
In systemic autoimmune diseases such as systemic lupus erythematosus (SLE), B cell tolerance is lost and there is a production of autoantibodies that drive pathology.
Nov 1, 2016 · "Our research group has been interested in B lymphocytes and what goes wrong in the regulation of different types of autoimmune disease," says Professor Mikael Karlsson at the Department...
Mikael Karlsson. Karolinska Institutet. ... IL-18 in inflammatory and autoimmune disease. SK Sedimbi, T Hägglöf, MCI Karlsson ... MCI Karlsson, S Wernersson, T Diaz ...
Cellular and Molecular Life Sciences. RevIew. IL‐18 in inflammatory and autoimmune disease. Saikiran K. Sedimbi · Thomas Hägglöf · Mikael C. I. Karlsson. Received: 8 April 2013 / Revised: 4 July 2013 / Accepted: 11 July 2013 / Published online: 27 July 2013 Springer Basel 2013. Abstract.
Apr 17, 2020 · The newly discovered mechanism is published in PNAS from research led by Dr. Saikiran Sedimbi and Prof. Mikael Karlsson. Autoimmune disease is a result of an imbalance of the immune system that includes breakdown of several mechanisms that normally prevent disease.
