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Jan 14, 2022 · The evidence generated by pivotal RCTs supports the use of triple therapy in patients who present for the first time and have severe airway obstruction, are symptomatic, have had frequent moderate or severe exacerbations in the previous year, and have peripheral eosinophilia.
- Dual Bronchodilator in the Era of Triple Therapy - PMC
Finally, in order to optimize pharmacotherapy in stable...
- Dual bronchodilator therapy for chronic obstructive pulmonary ...
Abstract. Purpose of review: Recent updates to the GOLD...
- When is dual bronchodilation indicated in COPD? - PMC
Dual bronchodilation may be suitable as a step-up approach...
- Dual Bronchodilator in the Era of Triple Therapy - PMC
Oct 28, 2020 · Finally, in order to optimize pharmacotherapy in stable COPD, we propose an algorithm on performing step-up of therapy from dual bronchodilation to triple therapy and step down from triple to double bronchodilation taking into account the extremely heterogeneous population of COPD patients.
- Andriana I Papaioannou, Stelios Loukides, Petros Bakakos, Epameinondas N Kosmas, Nikoletta Rovina, P...
- 10.2147/COPD.S273987
- 2020
- 2020
Abstract. Purpose of review: Recent updates to the GOLD guidelines emphasize the use of combination LABA and LAMA bronchodilators for patients with chronic obstructive pulmonary disease with persistent dyspnea despite monotherapy or frequent exacerbations despite LAMA monotherapy.
- Steven D. Deas, Nikhil Huprikar
- 2017
Oct 28, 2020 · Finally, in order to optimize pharmacotherapy in stable COPD, we propose an algorithm on performing step-up of therapy from dual bronchodilation to triple therapy and step down from triple to double bronchodilation taking into account the extremely heterogeneous population of COPD patients.
Aug 3, 2017 · Dual bronchodilation may be suitable as a step-up approach in those with persistent symptoms or exacerbations. Initial therapy with dual bronchodilation could be appropriate for some patients, particularly those at risk of exacerbation or with severe symptoms at diagnosis.
- Mike Thomas, David Mg Halpin, Marc Miravitlles
- 2017
Feb 19, 2018 · 1. Introduction. Dual bronchodilation therapy is the cornerstone for the treatment of chronic obstructive pulmonary disease (COPD) [1]. Combining a long-acting β 2 adrenoceptor (β 2 -AR) agonist (LABA) with a long-acting muscarinic antagonist (LAMA) in a fixed-dose combination (FDC) improves lung function, dyspnea, quality of life, and ...
Oct 28, 2020 · In this report, we aimed to provide a review of the current knowledge on the importance of dual bronchodilation on COPD patients and to compare its use with triple therapy, by covering a wide spectrum of topics.
