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Aug 26, 2021 · Diabetic peripheral neuropathy (DPN) is the most common complication of diabetes. At present, there is no comprehensive summary of the clinical trials related to DPN.
- Mengmeng Wang, Zepeng Zhang, Jia Mi, Guoqiang Wang, Lulu Tian, Yunyun Zhao, Xiaomin Li, Xiangyan Li,...
- 10.2147/JPR.S320364
- 2021
- J Pain Res. 2021; 14: 2651-2664.
Feb 3, 2022 · Many of the failed clinical trials occurred at the same time multiple, newer clinical trials were suggesting that glucose control alone was insufficient to prevent neuropathy in people with type 2 diabetes . There is now consensus that glycemic control alone cannot prevent the progression of DPN in patients with type 2 diabetes.
Oct 18, 2022 · In this article, we highlight five areas of recent updates in DPN: evolving biomarkers for early and accessible diagnosis, metabolic risk factors, innovations in clinical trials for painful diabetic neuropathy, genetic modifiers of disease risk, and recent therapeutic developments.
Jun 2, 2023 · Painful diabetic peripheral neuropathy (PDPN) is present in nearly a quarter of people with diabetes. It is estimated to affect over 100 million people worldwide. PDPN is associated with impaired daily functioning, depression, sleep disturbance, financial instability, and a decreased quality of life.
- 10.2147/DMSO.S370050
- 2023
May 28, 2021 · Diabetic sensorimotor peripheral neuropathy (DSPN) is a serious complication of diabetes mellitus and is associated with increased mortality, lower-limb amputations and distressing painful...
- Gordon Sloan, Dinesh Selvarajah, Dinesh Selvarajah, Solomon Tesfaye
- 2021
Feb 3, 2022 · Over the past decade, significant clinical trials have paved the way for prompt inclusion of high-frequency spinal cord stimulation within the painful diabetic peripheral neuropathy treatment algorithm. This article aims to provide an updated evidence-based approach for the management of painful diabetic peripheral neuropathy.
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Mar 13, 2024 · Abstract. Painful diabetic peripheral neuropathy (DPN) is a highly prevalent and disabling complication of diabetes that is often misdiagnosed and undertreated.
