Search results
Nov 16, 2019 · Trial Design and Oversight. We conducted this multicenter, randomized, parallel-group, open-label trial involving asymptomatic patients with very severe aortic stenosis who were candidates for...
- Predictors of Outcome in Severe, Asymptomatic Aortic Stenosis
The poor outcome of patients with symptomatic aortic...
- Transcatheter Aortic-Valve Replacement for Asymptomatic ...
At 75 centers in the United States and Canada, we randomly...
- Transcatheter or Surgical Treatment of Aortic-Valve Stenosis
Abstract. Background. Among low-risk patients with severe,...
- Predictors of Outcome in Severe, Asymptomatic Aortic Stenosis
Nov 13, 2021 · The AVATAR trial (Aortic Valve Replacement Versus Conservative Treatment in Asymptomatic Severe Aortic Stenosis) is an investigator-initiated international prospective randomized controlled trial that evaluated the safety and efficacy of early SAVR in the treatment of asymptomatic patients with severe AS, according to common criteria (valve ...
- Marko Banovic, Svetozar Putnik, Martin Penicka, Gheorghe Doros, Marek A. Deja, Radka Kockova, Martin...
- 2021
Oct 28, 2024 · At 75 centers in the United States and Canada, we randomly assigned, in a 1:1 ratio, patients with asymptomatic severe aortic stenosis to undergo early TAVR with transfemoral placement of a...
Apr 8, 2024 · Abstract. Background. Among low-risk patients with severe, symptomatic aortic stenosis who are eligible for both transcatheter aortic-valve implantation (TAVI) and surgical aortic-valve...
4 days ago · The Aortic Valve Replacement Versus Conservative Treatment in Asymptomatic Severe Aortic Stenosis (AVATAR) trial is an investigator-initiated, prospective, multinational, randomized, controlled, parallel-group, event-driven trial that compared the safety and efficacy of early surgery in the treatment of truly asymptomatic patients with severe AS and LV ejection fraction (LVEF) ≥ 50% vs. conservative treatment with watchful waiting strategy and AVR only after symptom onset, or other ...
Dec 29, 2023 · These patients had critical aortic stenosis with a mean aortic valve peak velocity of more than 5 m/s, meaning most would have met the Class IIb level recommendation for aortic valve intervention at trial inclusion. 2,3,6 The AVATAR trial demonstrated a long-term benefit in all-cause, but not cardiovascular, mortality, but also recruited a younger patient population that included patients with very severe aortic stenosis. Even after enriching for a high-risk population with myocardial ...
People also ask
Should aortic stenosis be treated in low-risk patients?
How many asymptomatic patients with severe aortic stenosis were screened?
Which operative procedures are associated with a recurrent aorta stenosis?
Does early aortic-valve replacement surgery reduce mortality in asymptomatic patients with stenosis?
Who is eligible for the aortic stenosis trial?
The EASY-AS trial will establish whether a strategy of early aortic valve replacement in asymptomatic patients with severe aortic stenosis reduces cardiovascular mortality or heart failure hospitalization and improves other important outcomes.
