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Jan 6, 2016 · 1 Altmetric. Metrics. Release of neurotransmitters occurs by opening of a fusion pore in a manner thought to be mediated by SNARE proteins, but whether the fusion pore is a lipidic or a...
- Satyan Sharma, Manfred Lindau
- 2016
Introduction. The first report indicating that synaptic transmission occurs in the form of discrete packages of neurotransmitter was published by Fatt and Katz in Nature (1950) with the title “ Some observations on biological noise ”.
- Satyan Sharma, Manfred Lindau, Manfred Lindau
- 10.1002/1873-3468.13160
- 2018
- 2018/11
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Release of neurotransmitters occurs by opening of a fusion pore thought be formed by action of SNARE proteins but if the fusion pore is a lipidic or proteinaceous structure is controversial. A new study employing very small nanodiscs shows that it is both.
- Satyan Sharma, Manfred Lindau
- 10.1038/nsmb.3157
- 2016
- 2016/01
View Satyan Sharma’s profile on LinkedIn, the world’s largest professional community. Satyan has 1 job listed on their profile. See the complete profile on LinkedIn and discover Satyan’s...
- GGDSD College Chandigarh
- Research Scholar
- Department of Sanskrit, Panjab University
Jun 25, 2016 · The results further pinpoint a hitherto unrecognized mechanism wherein TMDs of v-SNARE isoforms with a high content of ß-branched amino acids are employed for efficient fusion pore expansion of larger sized vesicles, suggesting a general physiological significance of TMD flexibility in exocytosis.
Satyan is well experienced and knowledgeable researcher in many areas of computational chemistry, including molecular dynamics simulations with enhanced sampling, coarse-grained simulations of...
- Uppsala University
