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Feb 2, 2024 · Disintegration test apparatus is widely used in pharmaceuticals to identify the disintegration properties of various types of tablets and capsules. The DT apparatus decides whether or not tablets or capsules disintegrate within a recommended time once placed in a liquid medium.
Disintegration Test. This test determines whether dosage forms such as tablets, capsules, boluses pessaries and suppositories disintegrate within a prescribed time when placed in a liquid medium under the prescribed experimental conditions.
Jun 3, 2023 · Disintegration is defined as that state in which no residue of the unit under test remains on the screen of the apparatus or, if a residue remains, it consists of fragments of disintegrated parts of tablets component parts such as insoluble coating of the tablets or of capsule shells, or of any melted fatty substance from the pessary or supposit...
In the pharmaceutical industry, drug dissolution testing is routinely used to provide critical in vitro drug release information for both quality control purposes, i.e., to assess batch-to-batch consistency of solid oral dosage forms such as tablets, and drug development, i.e., to predict in vivo drug release profiles. [1] .
This test is provided to determine whether tablets or capsules disintegrate within the prescribed time when placed in a liquid medium at the experimen-tal conditions presented below. FCompliance.
This test is provided to determine whether tablets or capsules disintegrate within the prescribed time when placed in a liquid medium under the experimental conditions presented below. For the purposes of this test disintegration does not imply complete dissolution of the unit or even of its active constituent.
This test is provided to determine whether tablets, capsules, or granules USP 1-Aug-2019 disintegrate within the prescribed time when placed in a liquid medium at the experimental conditions presented below.
Jun 10, 2004 · The revision to the harmonized standard for disintegration testing of pharmaceutical dosage forms has been approved by the Pharmacopeial Discussion Group (PDG) as described in the PDG sign-off cover sheet.
Mar 1, 2017 · The disintegration process is specifically critical for immediate-release dosage forms. Its mechanisms and the factors impacting disintegration are discussed and methods used to study the disintegration in-situ are presented.
ABSTRACT: Since its inception in the 1930s, disintegration testing has become an important quality control (QC) test in pharmaceutical industry, and disintegration test procedures for various dosage forms have been described by the different pharmacopoeias, with har-monization among them still not quite complete.
