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Thalidomide is a sedative drug discovered at the end of the 50s, which caused a worldwide tragedy. The drug has been prescribed to many pregnant women in order to relieve pregnancy nausea. It was later found that thalidomide caused irreversible damages to the fetus and thousands of children were born with severe congenital malformations.
Thalidomide is a type of targeted cancer drug. It’s a treatment for people not able to have high dose chemotherapy with a stem cell transplant for myeloma. If you’re having it as a treatment for myeloma you have thalidomide with other cancer drugs. Sometimes a doctor might prescribe thalidomide to treat myelofibrosis.
Aug 1, 2018 · Defects linked to disruption of key protein involved in fetal development. Finding will help guide development of new drugs. More than 60 years after the drug thalidomide caused birth defects in thousands of children whose mothers took the drug while pregnant, scientists at Dana-Farber Cancer Institute have solved a mystery that has lingered ...
Jan 1, 2022 · Introduction. Thalidomide remains one of the most notorious, and feared, drugs in the world. Its use to treat morning sickness in pregnant women, between 1957 and 1961, resulted in more than 10,000 children being born globally with severe and debilitating birth defects ( Vargesson, 2019 ).
Thalidomide is a targeted therapy drug. It works in different ways. Thalidomide can: help the immune system attack and destroy cancer cells (immune system modulator) kill or stop the growth of cancer cells (cancer growth inhibitor) block the development of new blood vessels which cancer cells need to grow and spread ( angiogenesis inhibitor ).
Mar 1, 2003 · Thalidomide was first introduced in West Germany in 1956 and in the rest of Europe, Australia, Canada, and South Africa in 1957. Fortuitously, its release in the United States was delayed by the Food and Drug Administration pending clarification of concerns regarding the results of neurotoxicological studies in animals.
Mar 23, 2020 · Thalidomide, a sedative sold by a German drugmaker, was said to relieve everything from anxiety to morning sickness, but it led to perhaps the greatest pharmaceutical scandal of all time. About ...
