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1. Dictionary

   hit

   /hɪt/

   verb

   • 1. bring one's hand or a tool or weapon into contact with (someone or something) quickly and forcefully: "the woman hit the mugger with her umbrella" Similar strikeslapsmackcuffpunchbeatthrashthumpbatterbelabourdrubhookpoundsmashslamweltpummelhammerbangknockswatwhipflogcanesucker-punchrain blows ongive someone a (good) beating/drubbingbox someone's earsinformal:whackwallopbashbiffbopcloutclipclobbersockswipecrownlickbeat the living daylights out ofgive someone a (good) hidingbelttanlay one onlay intopitch intolace intolet someone have itknock into the middle of next weeklamwhompdeckfloorzonkstick one ondotsloshtwatwellyslugboffbustwhaledongquiltking-hitliterary:smiteswingedated:bastebuffetbirch
   • ▪ accidentally strike (part of one's body) against something: "she fainted and hit her head on the metal bedstead"
   • ▪ (of a moving object or body) come into contact with (someone or something stationary) quickly and forcefully: "a car hit the barrier" Similar crash intorun intobang intosmash intosmack intoknock intobump intocannon intoplough intocollide withmeet head-onimpactinformal:barrel into
   • ▪ touch or press (part of a machine or other device) in order to work it: informal "he picked up the phone and hit several buttons"
   • 2. (of a missile or a person aiming one) strike (a target): "the sniper fired and hit a third man"
   • ▪ be suddenly and vividly realized by: "it hit her that I wanted to settle down here" Similar occur tostrikedawn oncome toenter one's headenter one's mindcross one's mindcome to mindspring to mindflash across one's mindcome into one's consciousness
   • 3. cause harm or distress to: "the area has been badly hit by pit closures" Similar affect badlydevastatedamageharmhurtruinleave a mark onhave a negative effect onhave a negative impact ondo harm toimpinge onupsetshattercrushshockoverwhelmtraumatizetouchmake sufferinformal:knock backknock for sixknock sidewaysknock the stuffing out ofOpposite have no effect on
   • ▪ (of a disaster) occur in and cause damage to (an area) suddenly: "the country was hit by a major earthquake"
   • ▪ attack and rob or kill: informal North American "if they're cops, maybe it's not a good idea to have them hit"
   • 4. reach (a particular level, point, or figure): informal "capital spending this year is likely to hit $1,800 million" Similar reachattaintoucharrive atget torise toclimb toachieveaccomplishgainsecureOpposite fall to
   • ▪ be affected by (an unfortunate and unexpected circumstance or event): "the opening of the town centre hit a snag"
   • ▪ arrive at or go to (a place): "it was still night when we hit the outskirts of London"
   • ▪ (of a product) become available and make an impact on: "the latest board game to hit the market"
   • ▪ take effect: "we sat waiting for the caffeine to hit"
   • ▪ give (someone) a dose of a drug or an alcoholic drink.
   • ▪ engage in a particular pursuit or activity with enthusiasm: "we went to Val d'Isère to hit the shops"
   • 5. propel (a ball) with a bat, racket, stick, etc. to score runs or points in a game.
   • ▪ score (a run or point) by hitting a ball with a bat, racket, stick, etc.: "he had hit 25 home runs"

   noun

   • 1. an instance of striking or being struck: "few structures can withstand a hit from a speeding car" Similar blowthumppunchknockbangthwackboxcuffslapsmackspanktapcrackstrokeweltimpactcollisionbumpcrashinformal:whackwallopbashbeltbiffcloutsockswipeclipclobbersloshboffbustslugwhaledongdated:buffet
   • ▪ a verbal attack: "I think people will try to take a hit at my credibility" Similar jibetauntjeersneerbarbcutting remarkbarbed remarkattackinsultinformal:digput-downcrackwisecrackOpposite compliment
   • ▪ a murder, typically one planned and carried out by a criminal organization: informal North American "some of the killings were contract hits"
   • ▪ short for base hit
   • 2. an instance of striking the target aimed at: "one of the bombers had scored a direct hit"
   • ▪ an instance of identifying an item of data which matches the requirements of a search.
   • ▪ an instance of a particular website being accessed by a user: "the site gets an average 350,000 hits a day"
   • 3. a successful venture, especially a film, pop record, or song: "he was the director of many big hits" Similar successbox-office successsell-outwinnertriumphsensationbestsellertour de forceinformal:knockoutcrowd-pullersmashsmash hitsmashersuperhitcrackerwowbiggieOpposite failureflop
   • ▪ a successful and popular person or thing: informal "he's proving to be a big hit with the fans" Similar successbox-office successsell-outwinnertriumphsensationbestsellertour de forceinformal:knockoutcrowd-pullersmashsmash hitsmashersuperhitcrackerwowbiggieOpposite failureflop
   • 4. a dose of a narcotic drug: informal "in another hour, I'll need another hit"

   Word Origin late Old Englishhittan (in the sense ‘come upon, find’), from Old Norse hitta ‘come upon, meet with’, of unknown origin.

   Scrabble Points: 6

   • H

     4

   • I

     1

   • T

     1

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2. my.clevelandclinic.org › health › diseasesHeparin Induced Thrombocytopenia: Symptoms & Treatment

   my.clevelandclinic.org › health › diseases

   • Cached

   Aug 12, 2022 · Heparin-induced thrombocytopenia (HIT) is a serious complication of taking the blood thinner heparin. With HIT, your immune system causes your platelets to clot in the presence of heparin, resulting in your platelet levels dropping. Without treatment, the clotting puts you at risk of developing life-threatening blood clots.

3. www.webmd.com › dvt › heparin-inducedHeparin-Induced Thrombocytopenia (HIT): What to Know - WebMD

   www.webmd.com › dvt › heparin-induced

   • Cached

   May 2, 2023 · What Is HIT? Heparin -induced thrombocytopenia (HIT) is a life-threatening condition that can happen to some people after they take a medicine called heparin, a blood -thinning drug that...

4. en.wikipedia.org › wiki › Heparin-inducedHeparin-induced thrombocytopenia - Wikipedia

   en.wikipedia.org › wiki › Heparin-induced

   • Cached

   Heparin-induced thrombocytopenia (HIT) is the development of thrombocytopenia (a low platelet count), due to the administration of various forms of heparin, an anticoagulant. HIT predisposes to thrombosis (the abnormal formation of blood clots inside a blood vessel).

5. emedicine.medscape.com › article › 1357846Heparin-Induced Thrombocytopenia: Practice Essentials ...

   emedicine.medscape.com › article › 1357846

   Sep 5, 2024 · Heparin-induced thrombocytopenia (HIT) is a complication of therapy with unfractionated heparin or low molecular weight heparin. HIT can occur irrespective of the dose or route of...

6. www.ncbi.nlm.nih.gov › pmc › articlesHeparin induced thrombocytopenia: diagnosis and management ...

   www.ncbi.nlm.nih.gov › pmc › articles

   Feb 27, 2007 · Heparin‐induced thrombocytopenia (HIT) is a potentially devastating immune mediated adverse drug reaction caused by the emergence of antibodies that activate platelets in the presence of heparin.

   • Author: I Ahmed, A Majeed, R Powell
   • DOI: 10.1136/pgmj.2007.059188

   • Publish Year: 2007
   • Publication: Postgrad Med J. 2007 Sep; 83(983): 575-582.

7. www.ncbi.nlm.nih.gov › books › NBK482330Heparin-Induced Thrombocytopenia - StatPearls - NCBI Bookshelf

   www.ncbi.nlm.nih.gov › books › NBK482330

   May 16, 2023 · Heparin-induced thrombocytopenia (HIT) is a severe complication that can occur in patients exposed to any form or amount of heparin products. A fall in platelet counts and a hypercoagulable state characterize HIT. Patients who experience HIT may also develop thromboembolic complications that are associated with significant morbidity and mortality.

8. www.uptodate.com › contents › management-of-heparinManagement of heparin-induced thrombocytopenia - UpToDate

   www.uptodate.com › contents › management-of-heparin

   • Cached

   Oct 27, 2023 · Heparin-induced thrombocytopenia (HIT) is a life-threatening complication of exposure to heparin (ie, unfractionated heparin, low molecular weight [LMW] heparin) that occurs in up to 5 percent of patients exposed, regardless of the dose, schedule, or route of administration.