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Click chemistry is an approach to chemical synthesis that emphasizes efficiency, simplicity, selectivity, and modularity in chemical processes used to join molecular building blocks.
Jun 23, 2021 · Click chemistry, as first articulated by Sharpless and colleagues in 2001, was born of a desire to harness the power of molecular assembly for the widest possible range of applications. The logic behind click chemistry is simple: (i) new molecular properties are needed everywhere; (ii) such properties can emerge from the joining of small ...
"Click Chemistry" is a term that was introduced by K. B. Sharpless in 2001 to describe reactions that are high yielding, wide in scope, create only byproducts that can be removed without chromatography, are stereospecific, simple to perform, and can be conducted in easily removable or benign solvents.
Click chemistry is a term that initially described reactions giving high yield and selectivity products by carbon-hetero bond formation reactions. The word “click” referred to easily joining molecular building blocks as two pieces of a seat belt buckle.
Jun 23, 2021 · As highlighted in the title of its first description in 2001, function is the point of click chemistry. Its success can be judged by how well it allows chemists and nonchemists alike to harness the power of molecular manipulation for the discovery and optimization of useful properties.
Click chemistry refers to a group of reactions that are fast, simple to use, easy to purify, versatile, regiospecific, and give high product yields. While there are a number of reactions that fulfill the criteria, the Huisgen 1,3-dipolar ...
Apr 26, 2023 · Designed to facilitate the facile and selective construction of molecules, click chemistry reactions are by design efficient, rapid, modular, clean and water compatible.
Click chemistry is an approach to the synthesis of drug-like molecules that can accelerate the drug discovery process by using a few practical and reliable reactions.
Oct 5, 2022 · Barry Sharpless and Morten Meldal have laid the foundation for a functional form of chemistry – click chemistry – in which molecular building blocks snap together quickly and efficiently. Carolyn Bertozzi has taken click chemistry to a new dimension and started utilising it in living organisms.
Jan 12, 2022 · We gave it an accessible name — click chemistry — meant to capture the satisfaction of easily connecting two objects with the snap of a push buckle. We highlighted an inspirational lesson from...
