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Soft tissue - Solitary fibrous tumor (extrapleural); fibroblastic tumor characterized by haphazardly arranged spindled to ovoid cells, prominent staghorn vasculature and NAB2-STAT6 gene rearrangement
Apr 27, 2023 · Solitary fibrous tumors (SFTs) of the CNS are spindle cell neoplasms with a wide range of histopathologic appearances and a pathognomonic NAB2::STAT6 fusion mutation with a characteristic immunophenotype. Essential features.
Sep 24, 2021 · Solitary fibrous tumor is a benign kidney tumor of patternless or storiform spindle cells with bland nuclear features, mixed with dense collagen.
Jun 10, 2021 · Solitary fibrous tumor (SFT) is a malignant condition that exhibits different clinical behaviors ranging from low to high aggressive SFT, with dedifferentiated SFT (DD-SFT) being the fastest-growing subtype.
Nov 2, 2018 · Solitary fibrous tumor (SFT) is a rare tumor of mesenchymal origin that account for less than 2% of all soft tissue masses. Initially identified in the pleura, SFT has been identified in multiple anatomic locations and can arise anywhere in the body.
Jun 10, 2021 · Solitary fibrous tumor (SFT) is a rare mesenchymal, ubiquitous tumor, with an incidence of 1 new case/million people/year. In the 2020 WHO classification, risk stratification models were recommended as a better tool to determine prognosis in SFT, to the detriment of "typical" or "malignant" classic ….
Apr 20, 2021 · Solitary Fibrous Tumor (SFT) is a distinct soft tissue neoplasm associated with NAB2-STAT6 gene fusion. It can involve a number of anatomic sites and exhibits a wide spectrum of histological features.
ICD-11: 2F75 & XH13Z3 - neoplasms of uncertain behavior of breast & aggressive fibromatosis. Epidemiology. < 0.2% of tumors of the breast. F > M, third through fifth decades. Reference: Breast Care (Basel) 2021;16:77. Sites. May be primary to the breast or be secondary extension into the breast from the chest wall. Pathophysiology.
Aug 30, 2021 · Although solitary fibrous tumors (SFTs) have an unpredictable evolution, some specific clinicopathologic factors have been associated with the final outcome. We retrieved clinical, pathological and molecular data of 97 patients with a histological diagnosis of SFT and Signal transducer and activator of transcription 6 (STAT6) positivity.
Jan 6, 2012 · Solitary fibrous tumor (SFT) is a mesenchymal tumor characterized by ovoid cells, branching blood vessels, stromal hyalinization, and CD34 immunoreactivity. Studies have shown loss of 13q in a group of morphologically similar entities, including cellular angiofibroma, mammary-type myofibroblastoma, and spindle cell lipoma.
