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Itai-itai disease (イタイイタイ病, itai-itai byō, "it hurts-it hurts disease") was the name given to the mass cadmium poisoning of Toyama Prefecture, Japan, starting around 1912. The term "itai-itai disease" was coined by locals for the severe pains (Japanese: 痛い itai) people with the condition felt in the spine and joints.
Aug 30, 2023 · Itai-itai disease, also known as "ouch-ouch disease," is a debilitating condition that is characterized by severe pain and bone deformities. The disease emerged in the mid-20th century in the Toyama Prefecture of Japan, primarily affecting individuals exposed to cadmium -contaminated water and rice crops.
Mar 23, 2016 · Itai-itai disease is a well-known health hazard induced by cadmium (Cd) that was first reported in the Cd-polluted Jinzu River basin of Toyama Prefecture, Japan.
Itai-itai disease is the most severe form of chronic cadmium intoxication. The first recognition occurred in Jinzu river, Toyama Prefecture, Japan ( 25 ). Two hypotheses have been proposed to explain bone lesion.
“Itai-itai disease”, a bone disease that occurred most frequently after the Second World War in Japan, is characterized by osteomalacia and renal tubular dysfunction and is an unusual disease. Cadmium may give rise to both osteomalacia and osteoporosis.
“Itai-itai” or ouch-ouch disease was first described in post-menopausal Japanese women exposed to excessive levels of cadmium over their lifetimes. The women were exposed through their diet because the region of Japan in which they resided was contaminated with cadmium (Ikeda et al. 2000; Watanabe et al. 2000).
Itai-itai disease was found in the cadmium (Cd) polluted Jinzu River basin in Toyama Prefecture, and has been generally recognized since the 1950's by the effort of inhabitants and Dr. Hagino who was a general practitioner with a private clinic in the polluted area.
The strange disease that appeared in the downstream basin of the Jinzu River around 1912 was called by locals "itai-itai byo" ("itai" being what Japanese people say when infilicate with pain and "byo" literally meaning disease). In came by this name because of the way victims cried out "itai-itai" under the excruciating pain they endured.
“Itai-itai disease”, a bone disease that occurred most frequently after the Second World War in Japan, is characterized by osteomalacia and renal tubular dysfunction and is an unusual disease. From: Journal of Trace Elements in Medicine and Biology , 2016
Sep 9, 2023 · Itai-itai disease is caused by environmental cadmium (Cd) pollution in the Jinzu River basin in Japan. To reduce the Cd contamination of rice, soil restoration of paddy fields was carried out.
