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Interpreting GO Enrichment Results. The Gene Ontology (GO) includes over tens of thousands of terms (functional categories), each tested individually for enrichment. These results are ranked, and only the top ones are displayed. Understanding this process is crucial for interpreting GO enrichment results.
Welcome to ShinyGO! Just paste your gene list to get enriched GO terms and othe pathways for over 200 plant and animal species. In addition, it also produces KEGG pathway diagrams with your genes highlighted, hierarchical clustering trees and networks summarizing overlapping terms/pathways, protein-protein interaction networks, gene characterristics plots, and enriched promoter motifs.
Enriched GO terms and pathways: In addition to the enrichment table, a set of plots are produced. If KEGG database is choosen, then enriched pathway diagrams are shown, with user's genes highlighted, like this one below: Many GO terms are related. Some are even redundant, like "cell cycle" and "cell cycle process".
Jul 5, 2023 · This tutorial explains how to perform Gene Ontology (GO) Enrichment Analysis using ShinyGO (a cloud R Shiny server). ShinyGO is an online graphical interface...
Dec 27, 2019 · In a GO cellular component enrichment analysis, Figure 1B and C shows that three terms related to cytoskeleton overlap in many genes. For species with fully sequenced genomes, ShinyGO plots the chromosomal locations of all the genes in the user’s list and conducts statistical analysis on the genomic features.
ShinyGO is an intuitive, graphical tool for enrichment analysis. Even though its species coverage is not as broad as DAVID, ShinyGO has more comprehensive ge...
Apr 25, 2023 · Gene ontology analysis is a powerful tool that enables researchers to uncover the biological function of genes, and it has become an essential component of g...
