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  1. Dictionary
    disregard
    /ˌdɪsrɪˈɡɑːd/

    verb

    • 1. pay no attention to; ignore: "the body of evidence is too substantial to disregard"

    noun

    • 1. the action or state of paying no attention to something: "blatant disregard for the law"

    More definitions, origin and scrabble points

  2. Oct 18, 2004 · Disregard limit Discussions about HPLC, CE, TLC, SFC, and other "liquid phase" separation techniques.

  3. Aug 11, 2014 · Hi I'm now analyzing chromatographic profile of the Peppermint oil using EP method, and I have some problems with understanding how to use disregard limit. In method is told: "The area of the principal peak in the chromatogram obtained with reference solution (b) (0.05%)" Solution (b) contain only 1 standart substance A. On chromatogram I see only 2 peak, Standart substance A and 1 impurity, with peak area 1.5 and 1.6. What I need to do next, and how to use this disregard limit?

  4. May 23, 2013 · LOQ Discussions about HPLC, CE, TLC, SFC, and other "liquid phase" separation techniques.

  5. Jul 12, 2016 · The ICH defines a Reporting Threshold as "A limit above which (ie greater than) the impurity should be reported" so in Empower 3 Impurity tab if I put 0.05 in the reporting threshold then Empower will flag any value GREATER THAN 0.05. But my impurity method states that "disregard any impurities less than 0.05%" so in order to include values of 0.05 upwards do I have to adjust the reporting threshold value to 0.04 to reflect this, similar to how RANGE in Empower treats the lower value as ...

  6. Nov 9, 2007 · Disregard limit & Method Validation Discussions about HPLC, CE, TLC, SFC, and other "liquid phase" separation techniques.

  7. Could you please advice in respect to an impurities calculation issue. We have developed / validated a method where impurities are calculated by the known formula: %imp= (Atest/Aref)* limit. Comparison of the % percentage for an unknown imp. with specific rrt with the %area presented in the chromatogram shows really high differences. Is this normal?? eg: impurity calculated with the method formula: 0.015% impurity as given in the chromatogram %area: 0.22!!! Forced degradation in acidic ...

  8. How would you define "Percentage Difference" Discussions about chromatography data systems, LIMS, controllers, computer issues and related topics.

  9. Aug 14, 2007 · Phenylephrin Hydrochloride Discussions about HPLC, CE, TLC, SFC, and other "liquid phase" separation techniques.

  10. Jun 7, 2017 · Failed System Suitability Test Discussions about HPLC, CE, TLC, SFC, and other "liquid phase" separation techniques.

  11. Aug 11, 2005 · Placebo peaks in related substances test Discussions about HPLC, CE, TLC, SFC, and other "liquid phase" separation techniques.