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  1. Without insulin, the amount of glucose entering the cells is reduced and the liver increases glucose production. 24. Three main causes of DKA are decreased or missed dose of insulin, illness or infection, and undiagnosed and untreated diabetes (DKA may be the initial manifestation of diabetes).

  2. Dec 11, 2012 · The document discusses the complications of diabetes mellitus, including both acute and chronic complications. Acute complications involve alterations in blood sugar levels, leading to hypoglycemia or hyperglycemia events like diabetic ketoacidosis or hyperglycemic hyperosmolar nonketotic syndrome.

  3. May 6, 2017 · This document discusses chronic complications of diabetes mellitus, focusing on microvascular complications including retinopathy, nephropathy, neuropathy, and foot disease as well as macrovascular complications affecting the coronary, cerebral, and peripheral circulations.

  4. Dec 19, 2019 · Complications of diabetes mellitus • Acute complications: • Ketoacidosis • The hyperglycemic hyperosmolar nonketotic syndrome • Hypoglycemia • Chronic complications: • Disorders of the microcirculation • Neuropathies • Nephropathies • Retinopathies • Macrovascular complications • Foot ulcers

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  5. HTN affects at least half of diabetes. In UKPDS, tight BP control (mean 144/82 mm Hg) achieved significant reductions in the risk of stroke (44%), heart failure (56%), and diabetes related deaths (32%), as well as reductions in microvascular complications (for example, 34% reduction in progression of retinopathy).

    • Retinopathy
  6. Diabetes and Mental Health. Bidirectional Relationship. Prevalence of Depression increased moderately in pre-diabetes patients and significantly in those with diabetes. Up to 40% of patients with diabetes experience clinically significant anxiety. Depression may increase risk of Type 2 DM by 60%.

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  8. 3 Pathophysiology of Diabetic Complications: Old Conundrum : why similar HgA1c in different folk give different risks I Metabolic Disorder Glucose, insulin hormones, enzymes, metabolites, etc (i.e., control) II Individual Susceptibility Genetic/ethnic?Acquired III Modulating Factors Hypertension, diet, smoking, etc., IR,Inflam Delayed ...