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Bert Vogelstein (born 1949) is director of the Ludwig Center, Clayton Professor of Oncology and Pathology and a Howard Hughes Medical Institute investigator at The Johns Hopkins Medical School and Sidney Kimmel Comprehensive Cancer Center.
Bert Vogelstein, M.D., was the first scientist to elucidate the molecular basis of a common human cancer. In particular, he and his colleagues have demonstrated that colorectal tumors result from the gradual accumulation of genetic alterations in specific oncogenes and tumor suppressor genes.
Bert Vogelstein is a renowned cancer researcher and a member of the National Academy of Sciences. He studies the genetics and immunotherapy of human cancer, and develops molecular genetic technologies for early detection and treatment.
- vogelbe@jhmi.edu
- 410-955-8878
- 410-955-0548
- Clayton Professor
Cited by. Year. A technique for radiolabeling DNA restriction endonuclease fragments to high specific activity. AP Feinberg, B Vogelstein. Analytical biochemistry 132 (1), 6-13. , 1983. 31194. 1983. A genetic model for colorectal tumorigenesis.
Dr. Bert Vogelstein was the first to elucidate the molecular basis of a common human cancer. His work on colorectal cancers forms the paradigm for much of modern cancer research, with profound implications for diagnostic and therapeutic strategies in the future.
The lab studies the genes and pathways underlying colon and rectal cancers, and how they can be prevented or treated. It focuses on the mutations, genetic instability, and clonal expansion of tumors, and applies this knowledge to patient management.
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Dr. Vogelstein is a cancer researcher and co-director of the Ludwig Center at Johns Hopkins University. He studies the molecular genetics of human cancer and develops new prevention and treatment strategies based on cancer driver genes.
