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Currently, three main theories have been proposed to explain the metastatic pathway of cancer: the epithelial-mesenchymal transition (EMT) and mesenchymal-epithelial transition (MET) hypothesis (1), the cancer stem cell hypothesis (2), and the macrophage–cancer cell fusion hybrid hypothesis (3).
Jul 4, 2024 · metastasis, migration and spread of cancerous cells from a tumour to distant sites in the body, resulting in the development of secondary tumours. Tumours that grow and spread aggressively in this manner are designated malignant, or cancerous.
- The Editors of Encyclopaedia Britannica
Nov 10, 2020 · This is how doctors can tell that it is cancer that has spread from another part of the body. Metastatic cancer has the same name as the primary cancer. For example, breast cancer that spreads to the lung is called metastatic breast cancer, not lung cancer. It is treated as stage IV breast cancer, not as lung cancer.
Aug 29, 2022 · Metastatic cancer cannot usually be cured, but it is treatable. For some people, it is possible to live with metastatic cancer for months or even years. The survival rate for metastasized cancer often depends on where the metastasis is located, how widespread it is, and what the primary cancer was.
Jan 9, 2023 · Continuing Education Activity. The lung is one of the most common sites of cancer metastasis. This activity will provide an overview of the common cancers that metastasize to the lung, the diagnostic work-up, and currently available treatment options.
- Asma Jamil, Anup Kasi
- 2023/01/09
Jan 21, 2021 · Metastasis formation is the major cause of death in most patients with cancer. Despite extensive research, targeting metastatic seeding and colonization is still an unresolved challenge. Only recently, attention has been drawn to the fact that metastasizing cancer cells selectively and dynamically a ….
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Jul 31, 2023 · Bone metastases affect survival rates ranging from 6 to 7 months in lung cancer to several years in the breast (19 to 25 months) or prostate cancer (12 to 53 months). Metastases may present with a single bone lesion, oligometastatic disease, multiple bone metastases, or visceral plus bone metastases.
