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Thalidomide is a known human teratogen and carries an extremely high risk of severe, life-threatening birth defects if administered during pregnancy. It causes skeletal deformities such as amelia (absence of legs and/or arms), absence of bones, and phocomelia (malformation of the limbs).
Thalidomide was introduced in 1953 as a tranquilizer, and was later marketed by the German pharmaceutical company Chemie Grünenthal under the trade name Contergan as a medication for anxiety, trouble sleeping, tension, and morning sickness.
May 28, 2024 · Thalidomide, compound in medicine initially used as a sedative and an antiemetic until the discovery that it caused severe fetal malformations. Thalidomide was developed in West Germany in the mid-1950s and was found to induce drowsiness and sleep. The drug appeared to be unusually safe, with few.
Thalidomide is a medication used to treat cancers, particularly newly diagnosed multiple myeloma, and erythema nodosum leprosum.
Apr 19, 2011 · Thalidomide was a widely used drug in the late 1950s and early 1960s for the treatment of nausea in pregnant women. It became apparent in the 1960s that thalidomide treatment resulted in severe birth defects in thousands of children.
Thalidomide was a widely used drug in the late 1950s and early 1960s for the treatment of nausea in pregnant women. It became apparent in the 1960s that thalidomide treatment resulted in severe birth defects in thousands of children.
Mar 23, 2020 · A pill treated as casually as aspirin. Federal inspectors uncovered evidence that thalidomide, which was to be sold under the brand name Kevadon, was passed among doctors and family members with...
Dec 11, 2019 · Thalidomide is a compound that was developed in the 1950s by the West German pharmaceutical company Chemie Grünenthal GmbH. It was originally intended as a sedative or tranquiliser but was soon used for treating a wide range of other conditions, including colds, flu, nausea and morning sickness in pregnant people.
Nov 2, 2021 · 1. Overview. Thalidomide is used around the world today to effectively treat inflammatory and cancer conditions. Yet, 60 years ago, it was withdrawn from the market. What do we know about its mechanisms of action and how safe it is? 2. History and withdrawal.
Perhaps no other drug in modern medicine rivals the dramatic revitalization of thalidomide. Originally marketed as a sedative, thalidomide gained immense popularity worldwide among pregnant women because of its effective anti-emetic properties in morning sickness.
