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Kiyoshi Nagai FRS (June 25, 1949 – September 27, 2019) was a Japanese structural biologist at the MRC Laboratory of Molecular Biology Cambridge, UK. He was known for his work on the mechanism of RNA splicing and structures of the spliceosome.
Oct 2, 2019 · Kiyoshi Nagai, Group Leader at the LMB and joint head of the Division of Structural Studies from 2001 to 2010, died on September 27 th 2019 after a short illness.
Kiyoshi Nagai was a structural biologist who studied the eukaryotic splicing machine, the spliceosome. He published several crystal and NMR structures of spliceosome components, and cryo-EM structures of the entire spliceosome at different stages of catalysis.
Mar 16, 2022 · Kiyoshi Nagai pioneered research in several areas of structural and molecular biology in an innovative and imaginative style. His initial work was on haemoglobin, the oxygen carrier in blood.
Kiyoshi Nagai has been discovering how proteins interact with RNA in ever-larger complexes for over three decades and, as some of his competitors have commented, he set the pace. His research culminated in visualization of the huge, dynamic spliceosome complex in the many different states it assumes while catalyzing pre-mRNA splicing.
- Chris Oubridge
- 2019
Mar 23, 2022 · Kiyoshi Nagai was a preeminent researcher at the LMB for over thirty years during which he was a global leader in the field of spliceosome research. His work culminated in a comprehensive understanding of how the spliceosome catalyses the intrinsic process of gene splicing within eukaryotic cells.
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Kiyoshi Nagai, group leader at the MRC Laboratory of Molecular Biology Cambridge, UK, sadly passed away on September 27, 2019 at the age of 70.
