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15 hours ago · Background Currently, treatment regimens for visceral leishmaniasis (VL) are limited because of the presence of numerous adverse effects. Nicotinamide, a readily available and cost-effective vitamin, has been widely acknowledged for its safety profile. Several studies have demonstrated the anti-leishmanial effects of nicotinamide in vitro. However, the potential role of nicotinamide in Leishmania infection in vivo remains elusive. Methods In this study, we assessed the efficacy of ...
4 days ago · It makes sense that Stahelski would be inclined to develop a remake since Debruge wrote, “the body count is up there in ‘John Wick’ territory.”. “When we made ‘Kill’ with Nikhil ...
2 days ago · Current evidence suggests that migraine headache is driven by activation of sensory nerve endings in the dura mater (10–14).However, efflux of cortical solutes to dura mater is limited by the arachnoid barrier layer, and these solutes only pass into dura mater along bridging veins draining into the the meningeal lymphatics and parasagittal spaces close to the major venous sinuses (15–19), thus restricting the contact between cerebrospinal fluid (CSF) solutes and afferents in dura mater.
1 day ago · Wetterthema Hurrikans und Klimawandel. Hurrikans und Klimawandel. Werden tropische Wirbelstürme im Zuge des Klimawandels stärker? Von Tim Staeger, ARD-Wetterkompetenzzentrum. Hurrikan BERYL ...
5 days ago · Warren Buffett, the legendary investor and chairman of Berkshire Hathaway, has once again made headlines with a revision to his posthumous philanthropic plans.
1 day ago · In a statement to Steve On Your Side, a spokesman for the Colorado Department of Revenue’s Taxation Division said the state has seen a historic number of tax returns filed -- about 3 million ...
1 day ago · Background Circulating proteins play essential roles in numerous complex diseases, yet our understanding of the genetic influences on inflammation and cardiovascular-related proteins in non-European isolated populations remains sparse. Here, we aimed to characterise the genetic architecture of plasma protein biomarkers in a Greenlandic population. Methods Using combined data from Greenlandic population cohorts (n=3,707 individuals), including genotypes and plasma proteomics (177 proteins ...
