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5 days ago · The compiled dataset included for each of the 207 patients was (i) information on the infecting Acinetobacter baumannii isolate (minimum inhibitory concentration, checkerboard assay data, and fitness in a murine model), (ii) colistin plasma concentrations and colistin and meropenem dosing history, and (iii) disease scores and demographics. The individual information was integrated into PKPD models, and the predicted change in bacterial count at 24 h for each patient, as well as patient ...
1 day ago · Teixobactin is bacteriocidal for numerous Gram-positive pathogens and has a spectacular minimal inhibitory concentration (MIC) of 5 ng/mL against C. difficile. Teixobactin also inhibits M. tuberculosis. With respect to its mechanism of action (MoA), teixobactin inhibits the peptidoglycan synthesis, but also interacts with the bacterial membrane.
2 days ago · a Dibucaine exhibits a 3 log 10 decrease (black arrows) in growth compared to its minimum inhibitory concentration (MIC) after 4 h at the MIC, and within 1 h at 2X and 4X the MIC.
1 day ago · Minimum inhibitory concentration (MIC) and minimum bactericidal concentration (MBC) MIC and MBC were determined according to a previously described method with minor modifications (Wiegand . MICs, MBCs, growth curves and time-kill curves
3 days ago · The Minimum Inhibitory Concentration (MIC) To assess the susceptibility of planktonic bacteria to four antibiotics (amoxicillin, clarithromycin, tetracycline, and levofloxacin), we employed the agar dilution method as previously described by Osato, Citation 24 with slight modifications for determining the MIC.
1 day ago · Since the activity of antibacterials depends frequently on its concentration, in vitro characterization of antibacterial activity commonly includes the determination of the minimum inhibitory concentration and minimum bactericidal concentration of an antibacterial.
3 days ago · The minimum inhibitory concentration (MIC) and minimal bactericidal concentration (MBC) were measured, and the bacterial growth curves of bacteria exposed to various concentrations of OCM were recorded. MIC and MBC values of OCM against C. acnes were 60 µg/mL and 180 µg/mL, respectively, with tetracycline used as a positive control. The MIC ...
