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5 days ago · Ali Yazdanyar 1, Joshua Baker 2, Katherine Wysham 3 and Michael Ward 4, 1 Perelman School of Medicine at the University of Pennsylvania, Philadelphia, PA, 2 Department of Medicine, Perelman School of Medicine University of Pennsylvania, Philadelphia, PA, 3 VA PUGET SOUND/UNIVERSITY OF WASHINGTON, Seattle, WA, 4 NIH, Bethesda, MD. Meeting: ACR ...
5 days ago · Inadequately treated pain disproportionally affects marginalized communities (i.e., identities pushed to the margins of society through systems of discrimination). 1, 2, 3 Clear evidence of racial bias in pain management exists across acute, chronic, and end-of-life contexts. 3, 4, 5 Compared to White people, those racialized as Black or African American are 29% less likely to receive treatment with opioids for similar conditions. 6 When opioids are prescribed, Black individuals are more ...
3 days ago · Sight is one of the key senses that humans use to assess their surroundings, and the retina is one of the most metabolically active organs in the human body. 1–4 The metabolism of the retina is finely controlled to allow for enough vascular supply to power the neural transmission of light.
2 days ago · Microglial cell iron load and inflammatory activation are significant hallmarks of late-stage Alzheimer’s disease (AD). In vitro, microglia preferentially upregulate the iron importer, divalent metal transporter 1 (DMT1, gene name Slc11a2) in response to inflammatory stimuli, and excess iron can augment cellular inflammation, suggesting a feed-forward loop between iron import mechanisms and inflammatory signaling.
5 days ago · The introduction of dual-energy X-ray absorptiometry (DXA) technology in the 1980s revolutionized the diagnosis, management and monitoring of osteoporosis, providing a clinical tool which is now available worldwide. However, DXA measurements are influenced by many technical factors, including the quality control procedures for the instrument, positioning of the patient, and approach to analysis. Reporting of DXA results may be confounded by factors such as selection of reference ranges for T ...
5 days ago · Labs at NIAMS. Our world-class investigators, staff, and trainees conduct research and clinical trials on the immune system, bones, joints, muscles, and skin. They develop novel diagnostic tools to analyze these systems and treatments for the diseases that affect them.
3 days ago · Behavioral factors increase the risk of contracting HIV. A comprehensive prevention services (CPS) intervention includes risk assessment and referral for those with confirmed risk. This project sought to assess the feasibility of an emergency department (ED)-based CPS program. A prospective cross-sectional assessment was conducted from October, 2021 through May, 2023, at a single ED in Birmingham, Alabama. Either of two screening methods were subjected to HIV negative adults: 1) manual chief ...
