Search results
14 hours ago · The secret lies in a unique substance called Limulus Amebocyte Lysate (LAL). This part of horseshoe crab blood has an extraordinary ability to detect bacterial endotoxins, which are harmful substances that can cause severe reactions in humans. The Industry
1 day ago · Horseshoe crab blood is a big deal because it contains a unique substance called Limulus Amebocyte Lysate (LAL). This stuff is like a superhero for detecting bacterial toxins in medical products. Imagine having a guardian that ensures vaccines, injectable drugs, and medical devices are safe from harmful bacteria.
5 hours ago · The smaller male horseshoe crabs would probably prefer some privacy when they stack up like this on a female, but unless you're a trained "citizen-scientist" who is "linked with Limulus" you may not have a clue that they're doing their parts to ensure the next generation
14 hours ago · Horseshoe crabs also play a crucial role in human health. Their unique blue blood contains Limulus amebocyte lysate, which is so sensitive to contaminants that it is used in vaccine testing. However, the widespread demand for its blood has led to unsustainable harvesting practices.
2 days ago · The Limulus amebocyte lysate, or LAL endotoxin test, is by far the most common assay used for endotoxin detection. LAL is extracted from the blood cells of the Atlantic horseshoe crab, Limulus polyphemus. Some assay formulations may use a similar lysate (TAL) extracted from the Asian Tachypleus species of crabs. Amebocyte lysates are used in ...
2 days ago · The pH was adjusted to between 7 and 8, and endotoxin concentration was determined using the Limulus Amebocyte Lysate (LAL) assay. The endotoxin concentration per cubic meter of air in the ward is calculated using the following formula: Concentration of airborne endotoxins per cubic meter of air = (1000 × endotoxin concentration in the sample × volume of the sampling medium) / (AGI airflow rate × sampling time).
5 days ago · Currently, recombinant reagents are considered alternative methods, requiring users to undergo extensive alternative method validation. However, with the implementation of USP <86>, users will be able to choose between traditional Limulus Amebocyte Lysate (LAL) and recombinant reagents without the need for this additional validation step.
