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3 days ago · In midstage testing, a combination of the NewAmsterdam drug with a generic cholesterol drug, ezetimibe, lowered LDL cholesterol by 63%. After peaking at 26.35 on Jan. 25, the stock tumbled as much ...
3 days ago · Dr C. Kathiresan Associate Professor & Head, Centre for Innovations and Appropriate Technology for Skills and Jobs and Centre for Research & Training Coordination & Networking
4 days ago · Beam also collaborates with other companies like Verve Therapeutics, giving them exclusive rights to some of Beam’s editing technologies for cardiovascular treatments. Permanent Cholesterol Reduction. Cardiologist Sekar Kathiresan has illuminated key genetic insights related to cardiovascular disease. Continuous low cholesterol levels ...
5 days ago · 2005 Nature’s randomised trials Lancet 366:1906–1908 [27] Emdin C. A. Khera A. V. Kathiresan S; 2017 Mendelian Randomization Jama 318:1925–1926 [28] Smith Davey; and Hemani G. 2014 Mendelian randomization: genetic anchors for causal inference in epidemiological studies Hum. Mol. Genet 23:R89–98 [29] Davies N. M. Holmes M. V. Davey Smith G
5 days ago · Jigarthanda Double X on Netflix. Jigarthanda DoubleX Aka Jigarthanda 2 is Written and Directed by Karthik Subbaraj, Ready for It’s OTT Release. Netflix Bagged the Digital Streaming Rights of The Film, Available in Tamil, Telugu, Kannada, Malayalam and Hindi.
5 days ago · Despite data suggesting that apolipoprotein B (apoB) measurement outperforms low-density lipoprotein cholesterol level measurement in predicting atherosclerotic cardiovascular disease risk, apoB measurement has not become widely adopted into routine clinical practice. One barrier for use of apoB measurement is lack of consistent guidance for clinicians on how to interpret and apply apoB results in clinical context. Whereas guidelines have often provided clear low-density lipoprotein ...
3 days ago · Human tissues accumulate somatic mutations over time, a process linked to aging. While the majority of these mutations hold limited or negligible significance, a subset may play a role in determining the survival efficiency of cells (1). Particularly, somatic mutations that amass in hematopoietic stem cells (HSCs) may confer a survival advantage, leading to the expansion of mutated cells within the bloodstream, a phenomenon recognized as clonal hematopoiesis of indeterminate potential (CHIP ...
