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1 day ago · Currently, aerodynamic environment prediction research into scramjet-propelled vehicles characterized by NACA0012 under hypersonic conditions is relatively sparse. Two-dimensional external flow field models are established, and then through validation tests, we perform a systematic investigation between simulation parameters and prediction accuracy, and an effective aerodynamic environment prediction simulation scheme under hypersonic conditions is proposed. Unlike under incompressible ...
3 days ago · What restricts Rme1 activity to biofilm growth conditions? Hypoxia may be a key factor. Sellam et al. showed that RME1 is induced rapidly when cells encounter hypoxic conditions . Synnott and colleagues found that RME1 expression depends upon Upc2, a central regulator of the hypoxic gene expression response .
3 days ago · Objectives Adipose tissue has been associated with knee osteoarthritis (KOA) pathogenesis, but the longitudinal changes in adipose tissue with KOA progression have not been carefully evaluated. This study aimed to determine if longitudinal changes of systemic and local adipose tissue is associated with radiographic progression of KOA. Methods This case-control study used data from the Osteoarthritis Initiative (OAI) and included 315 cases (all the right knees with a minimum of Kellgren ...
3 days ago · Background This study aimed to investigate functions of GLP-1R agonist by liraglutide (LIRA) and revealing the mechanism related to AGEs/RAGE in chondrocytes. Methods To illustrate potential effect of GLP-1R agonist on AGEs induced chondrocytes, chondrocytes were administrated by AGEs with LIRA and GLP-1R inhibitor exendin. Inflammatory factors were assessed using ELISA. Real-time PCR was used to evaluate the catabolic activity MMPs and ADAMTS mRNA level, as well as anabolic activity ...
1 day ago · Be ready to buy your new home! OPEN HOUSE: Saturday, August 3, 2024 11:00 AM - 12:30 PM. For Sale - 1160 Beacon #202, Brookline, MA - $2,249,000. View details, map and photos of this condo property with 2 bedrooms and 3 total baths. MLS# 73272395.
5 days ago · Over the next few years, her results in France would only get better. The next year, she claimed the final podium place, while in 2021, she placed 2nd, and in 2022, she won a stage. She finished on the podium in 3rd in the 2019 Tour of Flanders.
4 days ago · In vitro anti-inflammation efficiency of MENP. (A) Relative HIF-2α mRNA levels in inflammatory chondrocytes. (B and C) Expression levels of HIF-2α, MMP-13, and HIF-1α as determined by Western blot.
